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S100A6 expression in cutaneous smooth muscle neoplasms
APMIS, 2015The S100A6 protein is expressed in a variety of tissues and distinct staining patterns in S100A6 immunohistochemistry may be useful in the differential diagnosis of difficult lesions. We evaluated the staining pattern of the S100A6 antibody in 22 cases each of pilar leiomyoma (LM), angioleiomyoma (ALM), and cutaneous leiomyosarcoma (LMS).
Dirk M. Elston, Munir H. Idriss
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Smooth muscle tumours presenting as pleural neoplasms
Histopathology, 1995Five smooth muscle tumours presenting as pleural neoplasms are presented. The patients were three women and two men aged between 21 and 69 years (mean = 45 years). Clinically, one patient presented with chest pain, one with empyema and the other three were asymptomatic.
Michael N. Koss +5 more
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Smooth muscle neoplasms of the uterus
Current Opinion in Obstetrics and Gynecology, 1997Recent investigations, using DNA technology, of the molecular biology of smooth muscle tumours of the uterus have confirmed their monoclonality and have strengthened the view that oestrogen and oestrogen receptors play a major role in the pathogenesis of fibromyomata.
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Creatine kinase isoenzyme patterns in normal smooth muscle and smooth muscle neoplasms
Clinical Biochemistry, 1980The CK isoenzyme composition of leiomyoma tissue is predominantly CK-BB and similar to adjacent myometrium tissue, while the leiomyosarcoma revealed a lesser quantity of CK-BB, but a greater quantity of CK-MM. The reasons for the discrepancy between the two types of neoplasms is not clear, but may reflect the changes which occur when smooth muscle ...
W E DeCoteau +3 more
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Myometrium: Smooth Muscle Neoplasms
1983These tumours are so ubiquitous and well known that their general features require little comment. Histologically, they consist of fusiform smooth muscle cells with abundant eosinophilic cytoplasm and elongated, blunt-ended or tapering, nuclei which are arranged in bundles and whorls (Figure 18.1), the bundles often intersecting at right angles to each
H. Fox, C. H. Buckley
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Neoplasms and Mass Lesions Involving Muscle
1996The ability of MRI to demonstrate soft tissue lesions is unexcelled by other imaging methods as reported by many authors since 1984.1-13 The sensitivity and discriminating ability of MRI for muscle and connective tissue pathology is shown throughout this book.
Gerhard E. Maale, Paul T. Weatherall
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Embryonal rhabdomyosarcoma arising in the masseter muscle as a second malignant neoplasm
Journal of Oral and Maxillofacial Surgery, 1988A case is reported about a patient who was originally treated for bilateral retinoblastoma and subsequently developed an embryonal rhabdomyosarcoma in the masseter. Such patients have a genetic predisposition to a second malignancy that statistically far exceeds the rate for the general population.
Charles E. Tomich +3 more
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Smoothelin Is a Specific Marker for Smooth Muscle Neoplasms of the Gastrointestinal Tract
American Journal of Surgical Pathology, 2009Smoothelin is a smooth muscle-specific cytoskeletal protein exclusively found in differentiated smooth muscle cells. This contrasts with other smooth muscle proteins (eg, h-caldesmon, alpha-smooth muscle actin, desmin, smooth muscle myosin), which are expressed in proliferative (early) stages of smooth muscle development and occasionally in other cell ...
Dominique Coco +2 more
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Smooth Muscle Neoplasms of the Urinary Bladder
The American Journal of Surgical Pathology, 2002We report the clinicopathologic, immunohistochemical, and DNA ploidy findings of 18 leiomyosarcomas of the urinary bladder. In addition, we compare these malignant smooth muscle tumors with 10 cases of urinary bladder leiomyoma. The 14 male and four female patients with leiomyosarcoma ranged in age from 25 to 88 years (mean 64 years). The tumors ranged
Christine M. Lohse +4 more
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Beyond Smooth Muscle—Other Mesenchymal Neoplasms of the Uterus
Surgical Pathology Clinics, 2019Mesenchymal tumors of the uterus comprise a heterogeneous group of neoplasms of varied biologic potential. In addition to being host to several anatomically unique entities, the uterus may contain mesenchymal neoplasms typically found elsewhere in the body.
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