Results 51 to 60 of about 2,046,448 (371)

An unusual presentation of vaginal leiomyoma

Journal of Mid-Life Health, 2019
Leiomyomas are classified as benign mesenchymal neoplasms and consist of smooth muscle cells with variable amounts of fibrous stroma. The tumors occur most frequently in the uterus, affecting 20%–30% of women of reproductive age, but vaginal leiomyomas ...
Rahul R. Patil, Nikita R. Vijay, Sulbha Joshi   +2 more
doaj   +1 more source

Lipoleiomyoma of the Uterus [PDF]

, 2005
Lipoleiomyomas are uncommon benign neoplasms of uterus consisting of variable portions of mature lipocytes and smooth muscle cells. These tumours generally occur in asymptomatic obese perimenopausal or menopausal women.
Alper, Murat, Aylin Aksoy, Kamuran, Cukur, Selma, Kandemir Belenli, Olcay, Suna, Mazlume   +4 more
core  

Cellular deconvolution of GTEx tissues powers discovery of disease and cell-type associated regulatory variants. [PDF]

, 2020
The Genotype-Tissue Expression (GTEx) resource has provided insights into the regulatory impact of genetic variation on gene expression across human tissues; however, thus far has not considered how variation acts at the resolution of the different cell ...
D'Antonio, Matteo, D'Antonio-Chronowska, Agnieszka, Donovan, Margaret KR, Frazer, Kelly A   +3 more
core  

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Circumferential ankle leiomyoma with intratendinous involvement: A case report

Foot & Ankle Surgery: Techniques, Reports & Cases
Leiomyomas are mostly benign soft tissue neoplasms arising from smooth muscle. These neoplasms are infrequent in the lower extremity accounting for about 1.7 % of all benign soft tissue tumors.
Lauren Simon, DPM, David Gelbmann, DPM, Marsha A Apushkin, MD   +2 more
doaj   +1 more source

ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function

FEBS Letters, EarlyView.
The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran, Gloriana Campos, Natalya M. Wells, Khanhlinh Lambuu, Isabelle Draper, Christina A. Pacak, Peter B. Kang   +6 more
wiley   +1 more source

Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis

Nature Communications, 2019
Uterine leiomyomata (UL) or fibroids are neoplasms of the uterine smooth muscle associated with heavy menstrual bleeding and other female reproductive tract morbidity.
C. S. Gallagher, N. Mäkinen, H. R. Harris, N. Rahmioglu, O. Uimari, J. P. Cook, N. Shigesi, T. Ferreira, D. R. Velez-Edwards, T. L. Edwards, S. Mortlock, Z. Ruhioglu, F. Day, C. M. Becker, V. Karhunen, H. Martikainen, M.-R. Järvelin, R. M. Cantor, P. M. Ridker, K. L. Terry, J. E. Buring, S. D. Gordon, S. E. Medland, G. W. Montgomery, D. R. Nyholt, D. A. Hinds, J. Y. Tung, the 23andMe Research Team, J. R. B. Perry, P. A. Lind, J. N. Painter, N. G. Martin, A. P. Morris, D. I. Chasman, S. A. Missmer, K. T. Zondervan, C. C. Morton   +36 more
doaj   +1 more source

A Rare Massive Pulmonary Chondroid Hamartoma [PDF]

Journal of Clinical and Diagnostic Research, 2019
Hamartomas are disorganised but benign masses composed of cells indigenous to the involved site. They are the tumourous lesion consisting of anomalously arranged tissues that are components of the normal lung, such as cartilage, fat, smooth muscle, and ...
Nazneen Abdul Kader, Minnu khadeeja, PP Sathi   +2 more
doaj   +1 more source

Intramuscular (infiltrating) Lipoma [PDF]

, 2011
Intraoral lipomas are benign and relatively rare tumors, although they occur with higher frequencies in other areas, most especially the back, abdomen and shoulders of adults.
Kashyap, Bina, Naag, Ananth, Reddy, P Sridhar   +2 more
core   +1 more source

Adipocyte-Like Differentiation in a Posttreatment Embryonal Rhabdomyosarcoma. [PDF]

, 2015
We describe a 16-year-old boy with rhabdomyosarcoma, consistent with embryonal subtype, of the lower extremity who received systemic neoadjuvant chemotherapy and subsequent excision.
Balitzer, Dana, Horvai, Andrew E, McCalmont, Timothy H   +2 more
core   +4 more sources