Derangements of amino acids in cachectic skeletal muscle are caused by mitochondrial dysfunction
Journal of Cachexia, Sarcopenia and Muscle, 2020 Background Cachexia is the direct cause of at least 20% of cancer‐associated deaths. Muscle wasting in skeletal muscle results in weakness, immobility, and death secondary to impaired respiratory muscle function. Muscle proteins are massively degraded in
Thomas Kunzke +10 more
doaj +1 more source
Identification of mouse soleus muscle proteins altered in response to changes in gravity loading. [PDF]
Sci Rep, 2023 Ino Y +11 more
europepmc +1 more source
Muscle Fatigue from the Perspective of a Single Crossbridge [PDF]
, 2016 The repeated intense stimulation of skeletal muscle rapidly decreases its force- and motion-generating capacity. This type of fatigue can be temporally correlated with the accumulation of metabolic by-products, including phosphate (Pi) and protons (H ...
Debold, Edward Patrick +3 more
core +1 more source
Identification of Key Proteins Involved in Axon Guidance Related Disorders: A Systems Biology Approach [PDF]
arXiv, 2018 Axon guidance is a crucial process for growth of the central and peripheral nervous systems. In this study, 3 axon guidance related disorders, namely- Duane Retraction Syndrome (DRS) , Horizontal Gaze Palsy with Progressive Scoliosis (HGPPS) and Congenital fibrosis of the extraocular muscles type 3 (CFEOM3) were studied using various Systems Biology ...
arxiv
Single Muscle Fiber Proteomics Reveals Fiber-Type-Specific Features of Human Muscle Aging [PDF]
, 2017 Skeletal muscle is a key tissue in human aging, which affects different muscle fiber types unequally. We developed a highly sensitive single muscle fiber proteomics workflow to study human aging and show that the senescence of slow and fast muscle fibers
Ciciliot, Stefano +7 more
core +3 more sources
Scientific Reports, 2017 Muscle atrophy is one of the serious complications of chronic kidney disease (CKD). Dysregulation of mitochondrial quality control (MQC) process, including decrease mitochondrial biogenesis, impair mitochondrial dynamics and induce activation of ...
Dongtao Wang +6 more
doaj +1 more source
The Interplay Between Physical Activity, Protein Consumption, and Sleep Quality in Muscle Protein Synthesis [PDF]
arXivThis systematic review examines the synergistic and individual influences of resistance exercise, dietary protein supplementation, and sleep/recovery on muscle protein synthesis (MPS). Electronic databases such as Scopus, Google Scholar, and Web of Science were extensively used.
arxiv
Calsequestrins in skeletal and cardiac muscle from adult Danio rerio [PDF]
, 2015 Calsequestrin (Casq) is a high capacity, low affinity Ca2+-binding protein, critical for Ca2+-buffering in cardiac and skeletal muscle sarcoplasmic reticulum. All vertebrates have multiple genes encoding for different Casq isoforms.
Argenton, Francesco +6 more
core +1 more source
Investigating the migration hypothesis: Effects of trypsin-like protease on the quality of muscle proteins of red shrimp (Solenocera crassicornis) during cold storage. [PDF]
Food Chem X, 2023 Zhan F +5 more
europepmc +1 more source