This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen +7 more
wiley +1 more source
Malignant Hyperthermia, Rhabdomyolysis, and Critically Ill Myopathy in the Same Child Require Workup for Muscle Disease. [PDF]
Finsterer J.
europepmc +1 more source
A smart headband for multimodal physiological monitoring in human exercises
A novel smart headband incorporating a thermal‐sensation‐based electronic skin is presented for continuous and accurate multimodal physiological monitoring, including pulse waveforms, total metabolic energy expenditure, heart rate, and forehead temperature, across both static and dynamic daily activities.
Shiqiang Liu +7 more
wiley +1 more source
Anesthetic Management of a Giant Thymolipoma Causing Near Total Lung Collapse: A Case Report. [PDF]
Yadav M +4 more
europepmc +1 more source
Neuromorphic Motor Control with Electrolyte‐Gated Organic Synaptic Transistors
Electrolyte‐gated organic synaptic transistor (EGOST)‐based neuromorphic motor control systems integrate sensing, processing, and actuation by mimicking biological synapses. With advantages such as low power consumption, tunable synaptic plasticity, and mechanical flexibility, they are emerging as next‐generation core technologies for real‐time ...
Sung‐Hwan Kim +3 more
wiley +1 more source
Comparative effects of glycopyrrolate vs. atropine combined with neostigmine on heart rate dynamics and safety outcomes in pediatric patients: a prospective randomized controlled trial. [PDF]
Zou T +6 more
europepmc +1 more source
ABSTRACT Ensuring an adequate surgical proximal margin (SPM) is crucial in radical gastrectomy for gastric cancer. However, the lack of tactile feedback in laparoscopic distal gastrectomy (LDG) and robotic distal gastrectomy (RDG) poses challenges in precisely determining tumor boundaries, particularly in advanced gastric cancer, where tumor ...
Rie Makuuchi +9 more
wiley +1 more source
Selection of anesthetic agents for obstructive jaundice: An update for anesthesiologists. [PDF]
Li YQ, Zhou X, Cao Y, Long Y.
europepmc +1 more source
Centrally Acting Muscle Relaxant Activities of 2-Methyl-3-pyrrolidinopropiophenone Derivatives
M, Yamazaki +5 more
openaire +3 more sources
Abstract Pharyngeal high‐resolution manometry with impedance (P‐HRM‐I) is an established assessment method used to evaluate pharyngeal swallowing. It provides precise quantification of swallowing biomechanics that enable the detection of alterations in swallowing physiology.
Mistyka Schar +5 more
wiley +1 more source

