Results 11 to 20 of about 17,821 (298)

Basic Aspects of the Pharmacodynamics of Tolperisone, A Widely Applicable Centrally Acting Muscle Relaxant [PDF]

open access: yesThe Open Medicinal Chemistry Journal, 2014
Tolperisone (2-methyl-1-(4-methylphenyl)-3-piperidin-1-ylpropan-1-one hydro-chloride) was introduced in the clinical practice more than forty years ago and is still evaluated as a widely applicable compound in pathologically elevated skeletal muscle tone (spasticity) and related pains of different origin.
Bajaj P   +36 more
openaire   +6 more sources

Case report: A case of tetanus in a dog: cranial nerve involvement and imaging findings

open access: yesFrontiers in Veterinary Science, 2023
An 11 years old male Labrador cross presented with unilateral vestibular signs, ipsilateral facial paresis, moderate obtundation, ptyalism, and paraparesis.
Kylie Grant, Sam Long
doaj   +1 more source

The impact of high-risk medications on mortality risk among older adults with polypharmacy: evidence from the English Longitudinal Study of Ageing

open access: yesBMC Medicine, 2021
Background Polypharmacy is common among older people and is associated with an increased mortality risk. However, little is known about whether the mortality risk is related to specific medications among older adults with polypharmacy.
Yun-Ting Huang   +3 more
doaj   +1 more source

Potential Targets for Deprescribing in Medically Complex Older Adults with Suspected Cognitive Impairment

open access: yesGeriatrics, 2022
Deprescribing may be particularly beneficial in patients with medical complexity and suspected cognitive impairment (CI). We describe central nervous system (CNS) medication use and side effects in this population and explore the relationship between ...
Juliessa M. Pavon   +5 more
doaj   +1 more source

Experience with Tetanus in a Tertiary Care Hospital in Sudan: A Retrospective Review

open access: yesEmergency Medicine International, 2021
Introduction. Tetanus is still a major health issue, especially in rural areas, and is associated with high morbidity and mortality rate. This study was conducted to describe the pattern of presentation and treatment outcome among adult patients infected
Mumen Abdalazim Dafallah   +2 more
doaj   +1 more source

Perioperative and anesthetic deaths: toxicological and medico legal aspects [PDF]

open access: yes, 2019
Background: Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology.
Argo A.   +5 more
core   +1 more source

Non-intubated Thoracoscopic Surgery-Tips and Tricks From Anesthesiological Aspects: A Mini Review

open access: yesFrontiers in Surgery, 2022
BackgroundIn the last few decades, surgical techniques have been developed in thoracic surgery, and minimally invasive strategies such as multi-and uniportal video-assisted thoracic surgery (VATS) have become more favorable even for major pulmonary ...
Csongor Fabo   +7 more
doaj   +1 more source

CENTRALLY ACTING MUSCLE RELAXANTS IN TETANUS [PDF]

open access: yesBritish Journal of Pharmacology and Chemotherapy, 1961
The anti‐tetanus activity of a number of phenothiazine derivatives and other centrally acting muscle relaxants, such as mephenesin, dicyclopropyl ketoxime, 2‐amino‐6‐methylbenzothiazole and meprobamate, has been determined in rabbits with experimental local tetanus.
openaire   +3 more sources

Prescription medication use of United States military service members by therapeutic classification

open access: yesFrontiers in Pharmacology, 2022
Background: This cross-sectional study investigated the prevalence of, and factors associated with, filled prescription medications (FPMs) among United States (US) service members (SMs).Methods: A stratified random sample of active duty SMs from the Air ...
Joseph J. Knapik   +4 more
doaj   +1 more source

Silperisone: A Centrally Acting Muscle Relaxant [PDF]

open access: yesCNS Drug Reviews, 2006
ABSTRACTSilperisone is a tolperisone like organosilicon compound with centrally acting muscle relaxant properties. Studies in mice showed that silperisone may have less propensity to cause CNS depressant or motor side effects than tolperisone or other antispastic drugs.
openaire   +3 more sources

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