A novel β‐cyclodextrin/bile acid‐based slide‐ring hydrogel was prepared via precise host–guest recognition and photopolymerization. This smart hydrogel dressing exhibited skin‐adaptive mechanical properties, pH‐responsive antibacterial activity, and integrated multi‐signal sensing (temperature, blood, and pressure) for advanced wound management ...
Wen Huang +7 more
wiley +1 more source
Reducing the risk of anaphylaxis during anaesthesia: Guidelines for clinical practice [PDF]
Aberer, W. +58 more
core
Disrupted neurovascular coupling contributes to ovarian dysfunction in polycystic ovary syndrome. Using near‑infrared II long‑wavelength imaging, this study visualizes how electroacupuncture dynamically regulates ovarian blood vessels in vivo. Immediate and cumulative stimulation elicit distinct vascular responses via a Netrin‐1 dependent mechanism ...
Yicong Wang +15 more
wiley +1 more source
TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao +12 more
wiley +1 more source
Utilizing experimental design and desirability function in optimizing RP-HPLC method for simultaneous determination of some skeletal muscle relaxants and analgesics. [PDF]
Mozayad AN, Fouad MA, Elkady EF.
europepmc +1 more source
Fe‐Based Nanocrystalline Magnetic Shielding Cylinder with Subfemtotesla‐Level Magnetic Noise
Shields with low magnetic noise are achieved by integrating Fe‐based nanocrystalline magnetic shielding cylinders into shielding systems based on μ‐metal. Benefiting from high permeability and low loss factor, Fe‐based nanocrystalline magnetic shielding cylinders effectively suppress magnetic noise. Notably, the magnetic shielding cylinder with the ten‐
Peipei Shen +13 more
wiley +1 more source
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen +7 more
wiley +1 more source
Assessment of Physician Prescribing of Muscle Relaxants in the United States, 2005-2016.
Soprano SE +3 more
europepmc +1 more source
Neuromorphic Motor Control with Electrolyte‐Gated Organic Synaptic Transistors
Electrolyte‐gated organic synaptic transistor (EGOST)‐based neuromorphic motor control systems integrate sensing, processing, and actuation by mimicking biological synapses. With advantages such as low power consumption, tunable synaptic plasticity, and mechanical flexibility, they are emerging as next‐generation core technologies for real‐time ...
Sung‐Hwan Kim +3 more
wiley +1 more source
The Role of Muscle Relaxants – Spasmolytic (Thiocochlicoside) in Postoperative Pain Management after Mastectomy and Breast Reconstruction [PDF]
Bourazani M +6 more
europepmc +1 more source

