Results 321 to 330 of about 1,511,212 (387)
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Comparative Risk of Opioid Overdose With Concomitant Use of Prescription Opioids and Skeletal Muscle Relaxants

Neurology, 2022
Background and Objectives The concomitant use of prescription opioids and skeletal muscle relaxants has been associated with opioid overdose, but little data exist on the head-to-head safety of these drug combinations.
Nazleen F Khan   +5 more
semanticscholar   +1 more source

Risk of Opioid Overdose Associated With Concomitant Use of Opioids and Skeletal Muscle Relaxants: A Population‐Based Cohort Study

Clinical pharmacology and therapy, 2020
The recent opioid prescribing guideline cautions about the concomitant prescribing of opioids and skeletal muscle relaxants (SMRs) given the additive central nervous system depressant effect. However, the clinical relevance remains unclear.
Yan Li   +6 more
semanticscholar   +1 more source

Muscle relaxants

Best Practice & Research Clinical Anaesthesiology, 2003
Studies on the toxic effects of muscle relaxants are difficult to design because of the need for mechanical ventilation and, consequently, concomitant administration of anaesthetic drugs which may influence the results. The following overview shows that muscle relaxants are weak toxic agents with regard to their teratogenicity, carcinogenicity and ...
Sandra, Kampe   +2 more
openaire   +2 more sources

Muscle Relaxants

BASIC Essentials, 2018
Muscle relaxants may be needed, including benzodiazepines such as diazepam (Valium). For increased muscle tone (spasticity) Baclofen (Lioresal?) is a useful drug. Baclofen is a GABA-agonist, although its exact mechanism of action remains uncertain. It is
Carisoprodol Soma   +5 more
semanticscholar   +1 more source

Relaxation of diaphragm muscle

Journal of Applied Physiology, 1999
Relaxation is the process by which, after contraction, the muscle actively returns to its initial conditions of length and load. In rhythmically active muscles such as diaphragm, relaxation is of physiological importance because diaphragm must return to a relatively constant resting position at the end of each contraction-relaxation cycle.
Yves Lecarpentier   +2 more
openaire   +3 more sources

Allergy to muscle relaxants

Clinical Reviews in Allergy, 1991
With the now widespread and extensive use of muscle relaxant drugs in general anesthesia, a steadily increasing number of cases of anaphylactic-like reactions is being reported (1-3). Muscle relaxants seem to be responsible for half of the adverse reactions occurring during general anesthesia (4).
JoËlle Birnbaum, Daniel Vervloet
openaire   +3 more sources

Antinociceptive, Sedative and Muscle Relaxants Activity of Caralluma tuberculata N E Brown

, 2013
The current study was designed to assess the preliminary antinociceptive, sedative and muscle relaxants activates of crude extract and various solvent fractions of Caralluma tuberculata using established in-vivo protocols.
A. Rauf   +7 more
semanticscholar   +1 more source

Relaxation of smooth muscle

Canadian Journal of Physiology and Pharmacology, 1994
We have demonstrated that in dogs antigen sensitization results in alterations of contractile properties. These changes could account for the hyperresponsiveness reported in asthma. The failure of the muscle to relax could be another important factor responsible for maintaining high airway resistance.
Newman L. Stephens, H. Jiang
openaire   +3 more sources

Relaxing Factors in Muscle [PDF]

open access: possibleNature, 1953
ACCORDING to Szent-Gyorgyi1, muscle in the relaxed state is characterized by the dissociation of actomyosin into actin and myosin.
M. C. Goodall, Andrew G. Szent-Györgyi
openaire   +2 more sources

No supplemental muscle relaxants are required during propofol and remifentanil total intravenous anesthesia for laparoscopic pelvic surgery.

Journal of laparoendoscopic & advanced surgical techniques. Part A, 2009
BACKGROUND No administration of supplemental muscle relaxants may be beneficial to the recovery of the ambulatory laparoscopic surgery. For this study, we compared the cardiorespiratory factors during propofol and remifentanil anesthesia for laparoscopic
C. Paek, J. Yi, B. Lee, Jong-Man Kang
semanticscholar   +1 more source

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