British Journal of Pharmacology, EarlyView.Background and Purpose Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder caused primarily by loss‐of‐function mutations in the voltage‐gated potassium channel Kv1.1 (KCNA1). Small molecules that restore Kv1.1 activity hold promise as targeted therapies for EA1, yet current pharmacological strategies remain limited ...
Rían W. Manville +6 more
wiley +1 more source
PROPORTIONAL ELECTROMYOGRAPHIC CONTROL OF A BIONIC ARM IN A PARTICIPANT WITH CHRONIC HEMIPARESIS, MUSCLE SPASTICITY, AND IMPAIRED RANGE OF MOTION: A CASE STUDY. [PDF]
Myoelectr Control Upper Limb Prosthet Symp, 2022 Thomson CJ, George JA.
europepmc +1 more source
Input Visualizations to Track Health Data by Older Adults with Multiple Chronic Conditions
Computer Graphics Forum, EarlyView.Abstract Older adults living with multiple chronic conditions (MCC) can considerably benefit from collecting and reflecting on their health data. Many older adults collect their health data using various approaches, such as digital tools or handwritten notebooks.
Shri Harini Ramesh +4 more
wiley +1 more source
Developmental Medicine &Child Neurology, EarlyView.Abstract Aim To assess the clinical feasibility of lower‐limb pediatric exoskeleton‐assisted (Trexo Plus) physiotherapy for minimally ambulatory children at an outpatient center and a primary school. Secondary aims were to assess associated functional and goal‐based outcomes before and after Trexo‐based physiotherapy.
Stefanie S. Bradley +3 more
wiley +1 more source
Epidural Electrical Stimulation for Functional Recovery in Incomplete Spinal Cord Injury
Cyborg and Bionic SystemsEpidural electrical stimulation (EES) has emerged as a promising treatment for spinal cord injury (SCI). However, the therapeutic potential of EES in functional recovery following incomplete SCI remains limited, with few studies of a large sample size ...
Yihang Ren +8 more
doaj +1 more source
Anatomical locations of the motor endplates of sartorius muscle for botulinum toxin injections in treatment of muscle spasticity. [PDF]
Surg Radiol Anat, 2021 Yi KH +5 more
europepmc +1 more source
Developmental Medicine &Child Neurology, EarlyView.This study evaluated the Total Abnormality Score (TAS) from cMRI at term‐equivalent age as a predictor of cerebral palsy (CP) in 137 infants born preterm or with low birthweight. Infants who developed CP had significantly higher TAS values (median 11 vs 2), with a TAS cut‐off of 9.5 demonstrating high sensitivity (88.9%) and specificity (91.4%) for CP ...
Anne‐Kathrin Dathe +6 more
wiley +1 more source
Reliability and diagnostic accuracy of corrected slack angle derived from 2D-SWE in quantitating muscle spasticity of stroke patients. [PDF]
J Neuroeng Rehabil, 2022 Cao J +8 more
europepmc +1 more source
Variability of motor imagery in children with cerebral palsy examined using the Hand Laterality Test
Developmental Medicine &Child Neurology, EarlyView.Variability of motor imagery performance in children with cerebral palsy. Abstract Aim To examine motor imagery performance in children with cerebral palsy (CP) compared to typically developing children and develop a composite motor imagery score to differentiate between the two groups. Method In this cross‐sectional case–control study, 37 participants
Inbar Breuer Asher +3 more
wiley +1 more source
Botulinum toxin injection for Cockayne syndrome with muscle spasticity over bilateral lower limbs: A case report. [PDF]
World J Clin Cases, 2021 Hsu LC +7 more
europepmc +1 more source