Results 161 to 170 of about 50,607 (262)

Aminoacyl‐tRNA Synthetases: Variant Classification, Functional Assays, and Emerging Therapeutic Strategies

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Aminoacyl‐tRNA synthetases (aaRS) are essential enzymes that charge tRNAs with their corresponding amino acids, playing a critical role in protein synthesis. All 37 nuclear‐encoded ARS genes, comprising both cytosolic (ARS1) and mitochondrial (ARS2) isoforms, have now been linked to human disease.
M. I. Mendes, D. E. Smith, V. Spek, A. M. Bosch, W. E. Corpeleijn, M. Engelen, S. A. Fuchs, A. Hadchouel, I. U. Heinemann, R. H. Houtkooper, E. M. M. Hoytema van Konijnenburg, S. Kemp, M. Langeveld, C. D. M. Karnebeek, A. Pop, V. M. Siu, N. I. Wolf, G. S. Salomons   +17 more
wiley   +1 more source

A 25‐Year Bibliometric and Scientometric Analysis of Facial Paralysis Rehabilitation: Knowledge Structure, Influential Works, and Emerging Research Frontiers (2000–2025)

Microsurgery, Volume 46, Issue 4, May 2026.
ABSTRACT Background Facial paralysis rehabilitation has progressed substantially over the past two decades, yet the scientific landscape of this field remains highly fragmented across surgical, neurological, and rehabilitation disciplines. Despite growing clinical and technological advances—including neuromuscular retraining, chemodenervation ...
Mert Doğan, Fatma Ayvat
wiley   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Interrater Reliability of the Modified Tardieu Scale in the Assessment of Muscle Spasticity in Stroke Patients

Journal of Rehabilitation, 2008
Objective: Spasticity is one component of the upper motor neurone syndrome, which is characterised by a velocity dependent increase in the tonic stretch reflexes.
Nouroddin Nakhostin-Ansari, Soufia Naghdi, Gholam Reza O'liaei, Mahdi Abdolvahhab, Mahmoud Jalili, Shohreh Jalaei, Hossein Soltani-Nezhad   +6 more
doaj  

Higher THC Concentration Medicinal Cannabis Products Efficacy and Safety Considerations: A Rapid Review

Drug and Alcohol Review, Volume 45, Issue 4, May 2026.
ABSTRACT Issues Higher delta‐9‐tetrahydrocannabinol (THC) concentration medicinal cannabis products are characterised by a higher THC and minimal cannabidiol (CBD) content. This rapid review aims to systematically summarise and evaluate the available evidence regarding the efficacy and safety of higher THC potency medicinal cannabis products relevant ...
Myfanwy Graham, Dereje Assefa, Ngo Cong‐Lem, Suzanne Nielsen   +3 more
wiley   +1 more source

Predictors of Complications and Recurrence After Pressure Injury Reconstruction in Spinal Cord Injury: A Systematic Review and Meta‐Analysis

International Wound Journal, Volume 23, Issue 5, May 2026.
ABSTRACT Spinal cord injury (SCI) predisposes patients to pressure injuries (PIs) often requiring surgery. Multiple factors influence postoperative complications and recurrence, though their associations remain unclear. We performed a PRISMA‐guided systematic review and meta‐analysis to assess predictors of acute postoperative complications and PI ...
Marlynn P. Lopez, Katherine A. Kozlowski, Aneeq S. Chaudhry, Spencer K. Green, Diana B. Griffin, Tarifa H. Adam, Nicole C. Ontiveros, Allison B. Kessler, Rachna H. Soriano, Robert D. Galiano   +9 more
wiley   +1 more source

Multimodal machine learning to predict response to ultrasound-guided botulinum and vibration therapy in muscle spasticity a clinical and imaging correlation study. [PDF]

Front Bioeng Biotechnol
Chen H, Lin J, Lu H.
europepmc   +1 more source

A Personal Exploration of Oral Health in Amyotrophic Lateral Sclerosis (ALS) Through the Eyes of a Multifaceted Authority

Journal of Oral Rehabilitation, Volume 53, Issue 5, Page 1059-1064, May 2026.
This study resulted in agendas to improve oral health care, research, and education, advocating for a shift in ALS oral health care: from neglect to proactive integration. ABSTRACT Background and Objective Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease that impairs motor function, including oral musculature, complicating
Merel C. Verhoeff, Maurits K. A. van Selms, Frank Lobbezoo   +2 more
wiley   +1 more source

Non-invasive assessment of muscle spasticity in children with cerebral palsy undergoing botulinum toxin treatment using near-infrared spectroscopy. [PDF]

J Neuroeng Rehabil
Nourizadeh M, Juricic M, Begin J, Bektash L, Miller S, Mulpuri K, Shadgan B.   +6 more
europepmc   +1 more source

Botulinum Toxin Type A Possibly Affects Ca_v3.2 Calcium Channel Subunit in Rats with Spinal Cord Injury-Induced Muscle Spasticity. [PDF]

Drug Des Devel Ther, 2020
Ma K, Zhu D, Zhang C, Lv L.
europepmc   +1 more source