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Muscle histopathology in spastic cerebral palsy
Brain and Development, 1996We studied the histopathology of spastic muscles in patients with spastic cerebral palsy using specimens obtained from the gastrocnemius muscles during orthopedic operations. Though there was no disease-specific abnormality, we found changes in fiber type distribution, i.e., type-1 fiber predominance and type-2B fiber deficiency. These changes were not
J, Ito +5 more
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MUSCLE GROWTH IN NORMAL AND SPASTIC MICE
Developmental Medicine & Child Neurology, 1984SUMMARYLongitudinal muscle growth was studied in normal and spastic mice. Muscle growth takes place at the musculotendinous junction—the ‘muscle growth‐plate’. In spastic mice muscle growth is reduced by 45 per cent, resulting in contractures.RESUMECroissance musculaire chez les souris normales et spastiquesLa croissance longitudinale du muscle a ...
I, Ziv +3 more
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Treatment of spasticity with muscle afferent block
Neurology, 1999In 1924, Walshe1 first reported that intramuscular injection of diluted procaine reduced muscle rigidity in a patient with postencephalitic parkinsonism. Its mechanism of action was attributed to blockade of muscle afferents because the muscle motor response elicited by electric stimulation was unchanged.
T, Mezaki +4 more
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Effect of Muscle Biomechanics on the Quantification of Spasticity
Annals of Biomedical Engineering, 2001The impact of muscle biomechanics on spasticity was assessed by comparison of the reflex responses of the elbow and metacarpophalangeal (MCP) flexor muscles in individuals with chronic spastic hemiplegia following stroke. Specifically, methods were developed to quantify reflex responses and to normalize these responses for comparison across different ...
D G, Kamper, B D, Schmit, W Z, Rymer
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Pathology of Spastic Muscle in Cerebral Palsy
Clinical Orthopaedics and Related Research, 1979The histopathology of muscle in cerebral palsy has not been elucidated because correlated morphologic and biochemical data on normal pediatric muscles are insufficient to allow adequate correlation of pathologic findings. One hundred and eight muscle biopsies were taken during reconstructive operations on 85 patients.
M E, Castle, T A, Reyman, M, Schneider
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Muscle Elastography in Multiple Sclerosis Spasticity
Neurodegenerative Disease Management, 2016Ultrasound elastography is a novel imaging modality for evaluating the elasticity of biological tissues. The technique is widely used in oncology to detect and differentiate malignant lesions in soft tissues. Studies have explored use of ultrasound elastography to measure the mechanical properties of muscle in patients with multiple sclerosis ...
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A model of muscle spasticity in opensim
Gait & Posture, 2013Introduction: Computer simulations of human movement are commonly used to study normal and abnormal gait, for instance of subjects with spasticity. However, they generally do not include explicit models of spasticity. Our goal, therefore, was to develop a computer model of spasticity and to test this model by dynamic simulation of instrumented ...
Marjolein Van der Krogt +6 more
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Spastic Facial Muscle Disorders
2012Facial muscles are a group of striated muscles that, among other things, control facial expression and are innervated by the facial nerve (CNVII). In contrast, the nearby eyelid retractor muscle and masticator muscles are innervated by the oculomotor (CNIII) and mandibular branch of trigeminal nerve (CNV), respectively.
Juwan Park +2 more
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