Results 71 to 80 of about 1,566,168 (324)

Reliability and Validity of the Modified Heckmatt Scale in Evaluating Muscle Changes With Ultrasound in Spasticity

Archives of Rehabilitation Research and Clinical Translation, 2020
Objectives: To determine the reliability and validity of the Modified Heckmatt scale in assessing muscle echotexture in spasticity. Design: Prospective, observational, 2-center study. Two residents and 2 ultrasound experienced staff physicians each rated
Marisa C. Moreta, DO, Alana Fleet, MD, Rajiv Reebye, MD, FRCPC, Gina McKernan, PhD, Michael Berger, MD, PhD, FRCPC, Jordan Farag, MD, Michael C. Munin, MD   +6 more
doaj   +1 more source

Muscle Synergies in Cycling after Incomplete Spinal Cord Injury: Correlation with Clinical Measures of Motor Function and Spasticity

Frontiers in Human Neuroscience, 2016
Background: After incomplete spinal cord injury (iSCI), patients suffer important sensorimotor impairments, such as abnormal locomotion patterns and spasticity. Complementary to current clinical diagnostic procedures, the analysis of muscle synergies has
F. Barroso, D. Torricelli, E. Bravo-Esteban, Julian Taylor, J. Gómez-Soriano, C. Santos, J. Moreno, J. Pons   +7 more
semanticscholar   +1 more source

REEP1 Accumulation Disrupts ER Integrity and Drives Spinal Motoneuron Degeneration in Distal Hereditary Motor Neuropathy

Advanced Science, EarlyView.
REEP1 contributes to endoplasmic reticulum (ER) shaping. Variants either cause cortical motoneuron degeneration and hereditary spastic paraplegia (HSP) or spinal motoneuron degeneration and distal hereditary motor neuropathy (dHMN). Knockout causes less complex ER structures and cortical motoneuron loss.
Andrea Bock, Mona Schurig, Miles Willoughby, Andrea Mirecki, Eric Seemann, Kateryna Lohachova, Istvan Katona, Sonnhild Mittag, Lutz Liebmann, Patricia Franzka, Mehdi Heidari Horestani, Mukhran Khundadze, Thorsten Mosler, Timothy Louie, Marianne de Visser, Marian A. J. Weterman, Michael Kiehntopf, Christian Beetz, Sandor Nietzsche, Otmar Huber, Joachim Weis, Michael M. Kessels, Ramachandra M. Bhaskara, Britta Qualmann, Ivan Đikić, Christian A. Hübner   +25 more
wiley   +1 more source

The spasticity in the motor and functional disability in adults with post-stroke hemiparetic

Fisioterapia em Movimento
Introduction: Spasticity acts as a limiting factor in motor and functional recovery after Stroke, impairing the performance of daily living activities.
Roberta de Oliveira Cacho, Enio Walker Azevedo Cacho, Anderson Barbosa Loureiro, Gabriele Natane de Medeiros Cirne, Silvana Alves Pereira, Rodrigo Pegado de Abreu Freitas, Núbia Maria Freire Vieira Lima, Guilherme Borges   +7 more
doaj   +1 more source

Muscle Fatigue Enhance Beta Band EMG-EMG Coupling of Antagonistic Muscles in Patients With Post-stroke Spasticity

Frontiers in Bioengineering and Biotechnology, 2020
There is a significant influence of muscle fatigue on the coupling of antagonistic muscles while patients with post-stroke spasticity are characterized by abnormal antagonistic muscle coactivation activities. This study was designed to verify whether the
Le-Jun Wang, Le-Jun Wang, Xiao-Ming Yu, Qi-Neng Shao, Ce Wang, Hua Yang, Shang-Jun Huang, Wen-Xin Niu   +7 more
doaj   +1 more source

Effect of neurodevelopmental treatment-based physical therapy on the change of muscle strength, spasticity, and gross motor function in children with spastic cerebral palsy

Journal of Physical Therapy Science, 2017
[Purpose] This study aimed to investigate the effectiveness of neurodevelopmental treatment-based physical therapy on muscle tone, strength, and gross motor function in children with spastic cerebral palsy. [Subjects and Methods] One-hundred-seventy-five
E. Park, Won-Ho Kim
semanticscholar   +1 more source

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

Advanced Science, EarlyView.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr., Georgii B. Telegin, Aleksandr S. Chernov, Anna A. Kudriaeva, Alexey N. Minakov, Maksim V. Rodionov, Vitaly A. Kazakov, Viktor A. Palikov, Yuri M. Poluektov, Rustam H. Ziganshin, Daria A. Orlova, Alena S. Evpak, Daniil A. Barsuk, Fedor A. Mesheryakov, Aldo Spallone, Dmitry S. Asyutin, Igor N. Pronin, Nikolay A. Konovalov, Dmitri Yu Usachev, Alexander G. Gabibov, Alexander N. Konovalov   +20 more
wiley   +1 more source

A Wearable System Featuring Biomimetic Spatially Distributed Iontronic Sensing Array for Dynamic Monitoring of Deep Tissue Modulus

Advanced Science, EarlyView.
A fully wearable system enables real‐time, dynamic, and accurate monitoring of Young's modulus in multilayer tissues containing deep muscle. It demonstrates high accuracy and robustness across simulations, benchtop validations, and human testing. It quantifies edema severity and tracks muscle stiffness during rest, loaded elbow flexion, rope skipping ...
Zhenning Wang, Chaohua Fang, Ruoyu Sun, Chenghao Feng, Xiaoyuan Wang, Hao Bi, Yidan Wu, Jiangdong Gong, Yuyang Wang, Jiahao Guo, Yu Chang, Huizhi Wang, Tingrui Pan   +12 more
wiley   +1 more source

Quantitative evaluation for spasticity of calf muscle after botulinum toxin injection in patients with cerebral palsy: a pilot study

Journal of NeuroEngineering and Rehabilitation, 2016
Cerebral palsy (CP) is the most common pediatric disease to cause motor disability. Two common symptoms in CP are spasticity and contracture. If this occurred in the ankle plantar flexors of children with CP, it will impair their gait and active daily ...
Yu-Ching Lin, I-Ling Lin, T. Chou, Hsin-Min Lee   +3 more
semanticscholar   +1 more source

An ITPR1 Variant in the IP3‐ITPR1 Binding Pocket Associated With a Clinical Phenotype of Athetoid Cerebral Palsy

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT A de novo, missense variant in ITPR1‐inositol 1,4,5‐trisphosphate receptor type 1 (ITPR1), p.(Tyr567Cys), was identified by trio whole‐genome sequencing in an individual diagnosed with Spinocerebellar ataxia 29 (SCA29) who was affected by cerebral palsy and global developmental delay.
Thania Ordaz, Jagadish Chandrabose Sundaramurthi, Adam S. Arterbery, Anita M. Bagley, Michael A Gargano, Jeremy P Bauer, Daniel Danis, Philip Giampietro, Ellen Raney, Lauren Rekerle, Mallory Shingle, Jon R. Davids, Peter N. Robinson   +12 more
wiley   +1 more source