Results 71 to 80 of about 50,607 (262)

Spasticity Assessment Based on the Maximum Isometrics Voluntary Contraction of Upper Limb Muscles in Post-stroke Hemiplegia

Frontiers in Neurology, 2019
Background: The assessment of muscle properties is an essential prerequisite in the treatment of post-stroke patients with limb spasticity. Most existing spasticity assessment approaches do not consider the muscle activation with voluntary contraction ...
Hui Wang, Hui Wang, Pingao Huang, Pingao Huang, Xiangxin Li, Oluwarotimi Williams Samuel, Yun Xiang, Yun Xiang, Guanglin Li   +8 more
doaj   +1 more source

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

Advanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min, Nam Than, Yong Cheol Shin, Elif G. Ertugral, Chandrasekhar R. Kothapalli, Olumuyiwa Awoniyi, Hyun Jung Kim   +6 more
wiley   +1 more source

Towards remote monitoring and remotely supervised training [PDF]

, 2008
The growing number of elderly and people with chronic disorders in our western society puts such pressure on our healthcare system that innovative approaches are demanded to make our health care more effective and more efficient. One way of innovation of
Hermens, Hermie J.
core   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Research progress in the use of botulinum toxin type a for post-stroke spasticity rehabilitation: a narrative review

Annals of Medicine
Background Stroke is a leading cause of long-term disability and death worldwide. Spasticity after stroke seriously affects patients’ quality of life.
Qianwen Xu, Hongbo Xiao, Zongjun Zhu, Yuanyuan Guan, Ya Wang   +4 more
doaj   +1 more source

Effects of neuromuscular electrical stimulation on gait performance in chronic stroke with inadequate ankle control - A randomized controlled trial.

PLoS ONE, 2018
Neuromuscular electrical stimulation (NMES) has been used to improve muscle strength and decrease spasticity of the ankle joint in stroke patients.
Yea-Ru Yang, Pei-Ling Mi, Shih-Fong Huang, Shiu-Ling Chiu, Yan-Ci Liu, Ray-Yau Wang   +5 more
doaj   +1 more source

Results of selective dorsal rhizotomy in the treatment of local spasticity of lower limb extremities

Ukrainian Neurosurgical Journal, 2015
Aim: To develop diagnostic methods and to improve procedure of the dorsal selective rhizotomy (DSR) in patients with the local spasticity of lower extremities.Materials and methods: DSR (L2-S1) were performed in 12 patients with incurable ...
Leonid Pichkur, Iuriy Iaminskiy, Yuriy Lontkovsky   +2 more
doaj   +1 more source

A Robotic Test of Proprioception within the Hemiparetic Arm Post-stroke [PDF]

, 2014
Background: Proprioception plays important roles in planning and control of limb posture and movement. The impact of proprioceptive deficits on motor function post-stroke has been difficult to elucidate due to limitations in current tests of arm ...
Botzer, Lior, Ghez, Claude, Scheidt, Robert A., Simo, Lucia   +3 more
core   +3 more sources

The Faraday Scalpel: Electrochemical Nerve Lesioning Mechanisms Studied in Invertebrate Models

Advanced Science, EarlyView.
Direct‐current produces nerve lesioning through discrete electrochemical reactions. Using hypoxia‐sensitive locust nerves and hypoxia‐tolerant leech nerves, we map three injury pathways: cathodic oxygen reduction, cathodic alkalization, and anodic chloride oxidation. These findings establish electrochemical lesioning—the “Faraday Scalpel”—as a precise,
Petra Ondráčková, Jan Švec, Marie Jakešová, Jiří Ehlich, Imrich Gablech, Eric Daniel Głowacki   +5 more
wiley   +1 more source

The Short-Term Impact of Botulinum Neurotoxin-A on Muscle Morphology and Gait in Children with Spastic Cerebral Palsy

Toxins, 2022
Children with spastic cerebral palsy (SCP) are often treated with intramuscular Botulinum Neurotoxin type-A (BoNT-A). Recent studies demonstrated BoNT-A-induced muscle atrophy and variable effects on gait pathology. This group-matched controlled study in
Nicky Peeters, Eirini Papageorgiou, Britta Hanssen, Nathalie De Beukelaer, Lauraine Staut, Marc Degelaen, Christine Van den Broeck, Patrick Calders, Hilde Feys, Anja Van Campenhout, Kaat Desloovere   +10 more
doaj   +1 more source