Results 141 to 150 of about 983,311 (294)

Programmable Microgel Degradation in Dynamic Granular Hydrogels Guides Extracellular Matrix Assembly During Tissue Repair

Advanced Materials, EarlyView.
This study reports on the chemical modification of hyaluronic acid to create hydrogels with hydrolytic degradability ranging from 2–28 days. Granular hydrogels that undergo timed degradation to increase porosity enhance cell invasion and provisional ECM remodeling in a muscle injury model, leading to reduced fibrosis and improved regeneration ...
Zhiyuan Chen, Tuba Marjan, Xinyue Lu, Nicole E. Mertens, Keira Vesy, Dean E. Stornello, James F. Markworth, Taimoor H. Qazi   +7 more
wiley   +1 more source

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

Advanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren, Alex Wu, Lucas Ramirez, Yaqing Huang, Connor Amelung, Sophia Saxonhouse, Sharon Gerecht   +6 more
wiley   +1 more source

Wound complication after modified Ravitch for pectus excavatum: A case of conservative treatment enhanced by pectoralis muscle transposition. [PDF]

Int J Surg Case Rep, 2020
Aramini B, Morandi U, De Santis G, Brugioni L, Stefani A, Ruggiero C, Baccarani A.   +6 more
europepmc   +1 more source

A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration

Advanced Materials Interfaces, EarlyView.
The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani, Abu ul Hassan S. Rana, S. Sudheer Khan   +2 more
wiley   +1 more source

A Constraint‐Based Analytical Framework for Design‐Space Analysis and Material Screening of Tubular Multilayer Dielectric Elastomer Pumps for Extracorporeal Circulatory Applications

Advanced Materials Technologies, EarlyView.
A constraint‐based analytical framework maps the coupled effects of material properties, structural parameters, and operating conditions in tubular dielectric elastomer pumps for extracorporeal circulatory applications. The approach defines performance boundaries through mechanical, electrical, and hydraulic constraints and identifies feasible design ...
Yan Zhang, Amine Benouhiba, Yoan Civet, Yves Perriard   +3 more
wiley   +1 more source

Spatially Configurable Conformal Sensor Integration on an Ultra‐Fine Metallic Needle for Minimally Invasive Deep‐Tissue Oxygen Monitoring

Advanced Materials Technologies, EarlyView.
A multi‐point oxygen‐sensing ultra‐fine needle (MO‐UFN) is developed by conformally integrating a lithographically patterned flexible electrochemical sensor array onto a clinical acupuncture needle. The platform preserves an approximately 0.3 mm diameter while enabling spatially resolved oxygen profiling along the insertion pathway.
Yeju Seo, Jaeho Park, Yongrok Jeong, Ji‐Hwan Ha, Junseong Ahn, Jimin Gu, Su A Park, Ilwoo Jun, Kichul Lee, Inkyu Park   +9 more
wiley   +1 more source

3D‐Printed Actuator Powered by Liquid Crystal Elastomer Muscles at the Water–Air Interface

Advanced Materials Technologies, EarlyView.
Soft robots for unstructured environments require responsive, durable actuators. Liquid crystal elastomers (LCEs) provide large reversible deformations under thermal or optical stimuli. Direct ink writing enables fabrication of LCE actuators integrated with silicone, with mesogen chemistry and oligomers optimized for printable inks.
Cecilie Ryberg, Stefan Pendlmayr, Jan Skov Pedersen, Jens Vinge Nygaard, Jan P. F. Lagerwall, Brigitte Städler   +5 more
wiley   +1 more source

Modified semitendinosus muscle transposition to repair bilateral perineal hernias in dogs [PDF]

Perineal hernia (PH) resulting from a weakness and tear of the pelvic muscles of the diaphragm. Repair of the pelvic muscles by surgical repositioning is the curative treatment.
Stopiglia, Angelo João, Assumpção, Thais Cristine Alves de, Barbosa, Procássia Maria Lacerda, Fantoni, Denise Tabacchi, Queiroz, Genilson Fernandes de, Matera, Julia Maria   +5 more
core  

High‐Density Magnetomyography With Optical Magnetometers Reveals Spatiotemporal Patterns of Evoked Muscle Activity

Advanced Materials Technologies, EarlyView.
Optically pumped magnetometers are employed to contactlessly map the spatiotemporal dynamics of the magnetic field linked to electrical activity of a skeletal muscle in vivo. It is demonstrated that localization of the clinically relevant innervation zone is feasible using this non‐invasive magnetic measurement modality. ABSTRACT Magnetomyography (MMG)
Simon Nordenström, Victor Lebedev, Stefan Hartwig, Marlen Kruse, Santiago Rodriguez, Lukas Baier, Nima Noury, Thomas Klotz, Ahmet Doğukan Keleş, Justus Marquetand, Markus Siegel, Oliver Röhrle, Thomas Middelmann   +12 more
wiley   +1 more source