Reinforced Polymer–Nanoparticle Hydrogels for Subcutaneous and Sustained Delivery of Trastuzumab
Biologic therapy development is rapidly accelerating, requiring extended delivery formulation strategies. Supramolecular hydrogels and electrostatic complexation create subcutaneous depots that release clinically relevant trastuzumab doses in a controlled manner through simple component mixing without chemical modifications.
Giovanni Bovone+17 more
wiley +1 more source
Dissection and Whole-Mount Immunofluorescent Staining of Mouse Hind Paw Muscles for Neuromuscular Junction Analysis. [PDF]
Simkin RL+4 more
europepmc +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq+4 more
wiley +1 more source
Effects of a methionine deficiency on chicken tissue protein turnover: comparative analysis of methionine source. [PDF]
Conde-Aguilera JA+4 more
europepmc +1 more source
Tattoo Assisted Optical Sensor System for Multimodal Discrete Physiological Sensing
Conventional temporary tattoos can be used for improving the speckle imaging signal‐to‐noise ratio and stability of the specifically developed device for capturing skin motion related to physiological activities beneath the skin. This allows for sensing multimodal electrophysiological signals and physiological events from the skin consistent with ...
Zihuan Wu+5 more
wiley +1 more source
Analysis of Muscle Forces and Their Impact on Femoral Bone Stresses Using Response Surface Methodology (RSM). [PDF]
Habibi S+4 more
europepmc +1 more source
Rapid Deep Vat Printing Using Photoclickable Collagen‐Based Bioresins
Collagen‐based resin formulations based on thiol‐ene photoclick chemistry are demonstrated. These resins enable easy handleability under neutral conditions and further allow facile fabrication of multicellular tissue constructs via tomographic or FLight printing.
Michael Winkelbauer+8 more
wiley +1 more source
Ultrasonographic evaluation of masticatory and suprahyoid muscles in obstructive sleep apnea patients treated with mandibular advancement devices; a pilot study. [PDF]
Harati M+8 more
europepmc +1 more source
This study introduces a controllable degradation system for Mg‐based biomaterials using sputtering technology, marking a significant advancement in nerve regeneration research. The Mg‐sputtered nerve conduits demonstrate enhanced biocompatibility, biofunctionality, mechanical compatibility, and precise magnesium release, resulting in improved axonal ...
Hyewon Kim+12 more
wiley +1 more source