Results 231 to 240 of about 343,838 (345)

A multi‐omics investigation of sarcopenia and frailty: Integrating genomic, epigenomic and telomere length data

Experimental Physiology, EarlyView.
Abstract Sarcopenia and frailty are complex geriatric syndromes influenced by a combination of genetic and environmental factors. Recent studies suggest that specific genetic variants, DNA methylation patterns and shortened telomeres are associated with age‐related diseases and might contribute to the development of both sarcopenia and frailty. In this
Valentina Ginevičienė, Erinija Pranckevičienė, Alina Urnikytė, Laura Jurkūnaitė, Kristijona Gutauskaitė, Rūta Dadelienė, Justina Kilaitė, Ieva Eglė Jamontaitė, Asta Mastavičiūtė, Ildus I. Ahmetov, Vidmantas Alekna   +10 more
wiley   +1 more source

Editorial: Inflammation in muscular dystrophies: mediators, mechanisms, and therapeutics. [PDF]

Front Immunol
Villa C, Farini A, Torrente Y.
europepmc   +1 more source

CARE‐ing for concussions: Development of the Calgary Adapted aRm Ergometer (CARE) exertion test: A physiological alternative to the Calgary Concussion Cycle Test

Experimental Physiology, EarlyView.
Abstract Aerobic exercise testing helps facilitate recovery post‐concussion. Current protocols (Calgary Concussion Cycling Test: CCCT) are inaccessible for athletes with lower‐body impairments (i.e. Para athletes). This study compared physiological parameters for a novel arm crank test, the Calgary Adapted aRm Ergometer (CARE) test, with the CCCT ...
Jonathan D. Smirl, Joshua J. Burkart, Matthew G. Neill, Jean‐Michel Galarneau, Elizabeth K. S. Fletcher, Joel S. Burma, Nathan E. Johnson, John J. Leddy, Mohammad N. Haider, William M. Adams, Cheri Blauwet, Chantel T. Debert, Carolyn A. Emery   +12 more
wiley   +1 more source

Prevalence of Muscular Dystrophies: A Systematic Literature Review

Neuroepidemiology, 2014
A. Theadom, M. Rodrigues, R. Roxburgh, Shiavnthi Balalla, C. Higgins, R. Bhattacharjee, K. Jones, R. Krishnamurthi, V. Feigin   +8 more
semanticscholar   +1 more source

Preclinical quality, safety, and efficacy of a CGMP iPSC-derived myogenic progenitor product for the treatment of muscular dystrophies. [PDF]

Mol Ther
Azzag K, Magli A, Kiley J, Sumstad D, Kadidlo D, Crist SB, Norris B, Ahlquist A, Hocum Stone LL, Everett J, Shappa Faustich J, Seelig D, Rangarajan P, Kim H, Flory C, Bushman F, Ramachandran S, Kang PB, Schumacher RJ, Wagner JE, Kyba M, Graham ML, McKenna DH, Perlingeiro RCR.   +23 more
europepmc   +1 more source

Mitochondrial capacities and quality control following short‐ and long‐term weight restoration after simulated anorexia nervosa

Experimental Physiology, EarlyView.
Abstract Anorexia nervosa (AN) is a psychiatric disorder characterized by prolonged caloric restriction and skeletal muscle atrophy. Mitochondrial health is a key mediator of muscle function, yet the role of mitochondria during AN and following weight regain has not been investigated. The objective of this study was to evaluate mitochondrial capacities
Megan E. Rosa‐Caldwell, Toby L. Chambers, Lauren Breithaupt, Ruqaiza Muhyudin, Patience Salvalina Okoto, Sadie R. Thompson, Emily E. Rothacker, Claire Greenhill, Katie A. Wood, Kevin A. Murach, Sarah H. White‐Springer, Ursula B. Kaiser, Seward B. Rutkove   +12 more
wiley   +1 more source

Pain Experiences and Prescription Pain Medications Among People With Selected Muscular Dystrophies in the Muscular Dystrophy Surveillance, Tracking, and Research Network. [PDF]

Muscle Nerve
Suhl J, Conway KM, Thomas S, Rasmussen SA, Howard JF, Johnson NE, Romitti PA, Mathews KD, Muscular Dystrophy Surveillance, Tracking and Research Network (MD STARnet).   +9 more
europepmc   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source