Results 41 to 50 of about 32,608 (254)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

“The Impact of High-Intensity Insanity Training on Developing Selected Physical Abilities and Skill Performance on the Floor Exercise in Artistic Gymnastics” [PDF]

International Journal of Sports Science and Arts
The present study aims to investigate the effect of a training program using Insanity exercises on certain physical abilities—namely muscular strength, muscular endurance, cardiorespiratory endurance, flexibility, agility, balance, and neuromuscular ...
mervat salem, reem zoelfakar, soher elgendy, Donia Hegazy   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Optimizing Arm Muscle Endurance in Pencak Silat Athletes: Insights from a Literature Review

Tanjungpura Journal of Coaching Research
Background and Study Aim. Pencak Silat is a martial art that demands exceptional physical strength, agility, and endurance. Among these, arm muscle endurance plays an important role in performing effective offensive and defensive maneuvers. Improving arm
Jefrio Demitrimus Nubatonis, Sulistiyono Sulistiyono, Muhamad Husein, Irvan Septianto, Salmon Runesi, Dwi Manna Nazmi Zakiah, Julian Dewantara, Jihan Azrina, Syahrizal Islam, Vince Louisse D. Salacup   +9 more
doaj   +1 more source

AVALIAÇAO DO TREINAMENTO MUSCULAR RESPIRATÓRIO E DO TREINAMENTO FÍSICO EM INDIVÍDUOS SEDENTÁRIOS E EM ATLETAS

Revista Brasileira de Atividade Física e Saúde, 2012
O objetivo desse trabalho foi avaliar a força e a "endurance" muscular respiratória, através de um programo de treinamento muscular respiratório (TMR) e um programa de treinamento físico (PTF) realizado na bicicleta ergométrica.
Paulo Heraldo Costa do Valle, Dirceu Costa, Mauricio Jamami, Jorge Oishi, Vilmar Baldissera   +4 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Effects of twelve-week aerobic exercise on selected health-related physical fitness variables on Gonji preparatory school male students

East African Journal of Biophysical and Computational Sciences, 2022
The purpose of the present study was to investigate the effect of twelve-week aerobic exercise on health-related physical fitness components of grade eleven Gonjy preparatory school male students. The study employed an experimental research design.
Abdurahman Esleman, Bizuneh Yirga Geberemariam, Wondiye Aychiluhim   +2 more
doaj   +2 more sources

Yogic Practices as a Complementary Approach to Physical Fitness: An Intervention Study

Physical Education Theory and Methodology
Background. Yoga is an ancient practice that has gained attention for its potential benefits on muscular strength and endurance, flexibility, power, agility, balance, reaction time, and body mass index (BMI), making it an effective complementary approach
Tarak Nath Pramanik, Aminur Rahaman, Gopal Chandra Saha, Anupam Roy, Punam Pradhan   +4 more
doaj   +1 more source