Results 131 to 140 of about 9,516,409 (390)

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions

eLife, 2016
The transcription factor STAT5 is fundamental to the mammalian immune system. However, the relationship between its two paralogs, STAT5A and STAT5B, and the extent to which they are functionally distinct, remain uncertain.
Alejandro Villarino, Arian Laurence, Gertraud W Robinson, Michael Bonelli, Barbara Dema, Behdad Afzali, Han-Yu Shih, Hong-Wei Sun, Stephen R Brooks, Lothar Hennighausen, Yuka Kanno, John J O'Shea   +11 more
doaj   +1 more source

Autoimmune and rheumatic musculoskeletal diseases as a consequence of SARS-CoV-2 infection and its treatment

Rheumatology International, 2020
The coronavirus disease-2019 (COVID-19) pandemic is likely to pose new challenges to the rheumatology community in the near and distant future. Some of the challenges, like the severity of COVID-19 among patients on immunosuppressive agents, are ...
Sanket Shah, D. Danda, C. Kavadichanda, S. Das, M. Adarsh, V. Negi   +5 more
semanticscholar   +1 more source

An Animal‐Free Patient‐Derived Tissue‐Mimetic Biochip Model of the Human Synovial Membrane for Human‐Relevant Osteoarthritis Research

Advanced Healthcare Materials, EarlyView.
Reihs et al. present the development of a humanized, animal‐free synovial membrane model for osteoarthritis. Methods include 3D biochip cultures of human‐primary OA synoviocytes with matrix and serum surrogates. Results show replication of synovial architecture and increased Yap1 expression.
Eva I. Reihs, Alexander Stoegner, Mateo G. Vasconez Martínez, Markus M. Schreiner, Melanie Cezanne, Ruth Gruebl‐Barabas, Bettina Rodriguez‐Molina, Juergen Alphonsus, Silvia Hayer, Richard Lass, Iris Gerner, Florien Jenner, Wolfgang Holnthoner, Stefan Toegel, Peter Ertl, Hans P. Kiener, Reinhard Windhager, Mario Rothbauer   +17 more
wiley   +1 more source

Process and Analysis of Kidney Infiltrates by Flow Cytometry from Murine Lupus Nephritis

Bio-Protocol, 2012
Methods for the isolation and characterization of mononuclear phagocytes from the kidneys of mice with SLE are essential to understand the patho-physiology of the disease. Activation of these cells is associated with the onset of clinical disease in mice
Ramalingam Bethunaickan, Anne Davidson
doaj   +1 more source

Omentin: a biomarker of cardiovascular risk in individuals with axial spondyloarthritis

Scientific Reports, 2020
Cardiovascular (CV) disease is the main cause of mortality in axial spondyloarthritis (axSpA). CV risk is enhanced by dysregulation of adipokines. Low omentin levels were associated with metabolic dysfunction and CV disease in conditions different from ...
Fernanda Genre, Javier Rueda-Gotor, Sara Remuzgo-Martínez, Verónica Pulito-Cueto, Alfonso Corrales, Verónica Mijares, Leticia Lera-Gómez, Virginia Portilla, Rosa Expósito, Cristina Mata, Ricardo Blanco, Javier Llorca, Vanesa Hernández-Hernández, Esther Vicente, Cristina Fernández-Carballido, María Paz Martínez-Vidal, David Castro-Corredor, Joaquín Anino-Fernández, Carlos Rodríguez-Lozano, Oreste Gualillo, Juan Carlos Quevedo-Abeledo, Santos Castañeda, Iván Ferraz-Amaro, Raquel López-Mejías, Miguel Á. González-Gay   +24 more
doaj   +1 more source

Conditioned Media from Mechanically Stimulated Macrophages Upregulate Osteogenic Genes in Human Mesenchymal Stromal Cells

Advanced Healthcare Materials, EarlyView.
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex, Ursula Menzel, Yann Ladner, Angela R. Armiento, Martin J. Stoddart   +4 more
wiley   +1 more source

Toward Noninvasively Imaging pH at the Surface of Implanted Orthopedic Devices in Live Rabbits Using X‐ray Excited Luminescence Chemical Imaging

Advanced Healthcare Materials, EarlyView.
Imaging pH in a live rabbit at the surface of a sensor‐coated titanium plate using X‐ray excited luminescent chemical imaging (XELCI). A raster scanning X‐ray beam generates radioluminescence from a spot on the sensor, and the luminescence passes through the tissue and is collected at two wavelengths to determine local pH.
Unaiza Uzair, Fenglin Wang, Donald Benza, Yash S. Raval, Sriparna Bhattacharya, Tzuen‐Rong J. Tzeng, Jeffrey N. Anker   +6 more
wiley   +1 more source

Isolation of Dendritic Cells and Macrophages from the Murine Kidneys of Lupus by Cell Sorter

Bio-Protocol, 2012
Methods for the isolation and characterization of mononuclear phagocytes from the kidneys of mice with SLE are essential to understand the patho-physiology of the disease. Activation of these cells is associated with the onset of clinical disease in mice
Ramalingam Bethunaickan, Anne Davidson
doaj   +1 more source

The Cost of Care: New Insights into Healthcare Spending Growth [PDF]

, 2017
[Excerpt] The Bureau of Labor Statistics (BLS) is celebrating the first anniversary of experimental disease-based price indexes, which adjust expenditures on disease for inflation.
Bradley, Ralph
core   +1 more source