Results 161 to 170 of about 380,196 (292)

Understanding the Twentieth Century Decline in Chronic Conditions Among Older Men [PDF]

I use a sample of Union Army veterans to trace the impact of a high infant mortality rate in area of enlistment, such infectious disease as acute respiratory infections, measles, typhoid fever, tuberculosis, rheumatic fever, diarrhea, and malaria while ...
Dora L. Costa
core  

Anthocyanins and musculoskeletal diseases: mechanisms and therapeutic potential. [PDF]

Front Nutr
Lv X, Zhao XP, Li WC, Xing NF, Zong KQ, Zhai Y, Yang SL, Zhang JY, Liu X.   +8 more
europepmc   +1 more source

Tumor Extracellular Vesicles lncOSLMT Drives Lung Inflammatory Premetastatic Niche Formation in Osteosarcoma via m6A‐Dependent hnRNPA2B1/COX‐2 Axis

Advanced Science, EarlyView.
Tumor‐derived extracellular vesicles program inflammatory lung premetastatic niches through selective delivery of long noncoding RNAs. This work reveals EVs‐associated lncOSLMT as a key driver of lung fibroblast activation via m6A‐dependent PTGS2 stabilization.
Hongbo Li, Zehao Guo, Yutong Zou, Jiongfeng Zhang, Jixiang Shi, Xihong Fu, Jian Tu, Hao Yao, Xuanxuan Lu, Lili Wen, Xianbiao Xie   +10 more
wiley   +1 more source

Revisiting the mortality of France and Italy with the multiple-cause-of-death approach [PDF]

In this paper, we use the multiple cause-of-death approach to compare the mortality profiles of France and Italy in 2003. Our analysis leads to a substantial re-evaluation of the role played by certain conditions in the process leading to death ...
Aline Desesquelles, France Meslé, Luisa Frova, Marilena Pappagallo, Michele Antonio Salvatore, Monica Pace, Viviana Egidi   +6 more
core  

Emerging concepts in osteoarthritis and musculoskeletal diseases: Insights from the University of Debrecen Musculoskeletal Symposium 2025. [PDF]

Osteoarthr Cartil Open
Kovács P, Vágó J, Mobasheri A, Jenei-Lanzl Z, Zaucke F, Madry H, Csernoch L, Szekanecz Z, Szondy Z, Szöőr Á, Szatmari I, Oláh T, Matta C.   +12 more
europepmc   +1 more source

Advancing the Tendinopathy Triad: Comment on “Tendinopathy: The Interplay Between Mechanical Stress, Inflammation, and Vascularity”

Advanced Science, EarlyView.
Abstract Building upon the integrative framework of tendinopathy proposed by Gehwolf et al.—which elegantly connects mechanical stress, inflammation, and vascularity—this commentary extends the discussion by introducing novel mechanistic insights and future research directions that move beyond the established triad. A paradigm shift is proposed ...
DuJiang Yang, Jiexiang Yang, Shuang Wang, GuoYou Wang   +3 more
wiley   +1 more source

Musculoskeletal Diseases: From Molecular Basis to Therapy (Volume II). [PDF]

Biomedicines
Belluzzi E, Pozzuoli A, Ruggieri P.
europepmc   +1 more source

Spatial Transcriptomics of TMJ Reveals a Remodeling Fibroblast‐Immune Microenvironment Driving Arthritis Pain

Advanced Science, EarlyView.
Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin, Supawadee Jariyasakulroj, Yang Shu, Jingyi Chen, Qing Chang, Pao‐Fen Ko, Yuyueyang Qiu, Feixiang Chen, David Ahn, Zhen Zhao, Jian‐Fu Chen   +10 more
wiley   +1 more source

Instruments for measuring fatigue in people with rheumatic and musculoskeletal diseases: a systematic review of measurement properties. [PDF]

RMD Open
Santos EJF, Farisogullari B, Fishpool K, Young G, Ciurtin C, Cramp F, Erhieyovwe EO, Macfarlane GJ, Pearson J, Dures E, Machado PM.   +10 more
europepmc   +1 more source

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source