Results 171 to 180 of about 380,196 (292)

New horizons in spine research: Intervertebral disc repair and regeneration. [PDF]

, 2017
Iatridis, James C, Kandel, Rita, Kang, James, Risbud, Makarand V.   +3 more
core   +2 more sources

Short-term effects of ambient air pollution on musculoskeletal diseases in Yangzhou during 2019-2022. [PDF]

BMC Public Health
Zhang H, Wang B, Xiong W, Xia J, Zhao C, Dong R, Yin L, Wang Q, Zhang K.   +8 more
europepmc   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Lactylation Reprogramming in the Bone Infection Microenvironment Identifies PGK1 K361 as a Potential Therapeutic Target for Osteogenic Dysfunction

Advanced Science, EarlyView.
Staphylococcus aureus (S. aureus) infection creates a high‐lactate microenvironment, promoting p300‐mediated lactylation of PGK1 at lysine 361 (K361). Lactylated PGK1 translocates to the mitochondrial outer membrane and interacts with VDAC3. This interaction triggers FtMt downregulation, iron accumulation, and excessive PINK1/Parkin‐mediated mitophagy,
Han‐jun Qin, Si‐ying He, Ting‐hui Xiao, Da‐mao Dai, Xin‐jia Hu, Nan Jiang   +5 more
wiley   +1 more source

Musculoskeletal Diseases in Adolescence

Journal of the Royal College of Physicians of London, 2000
J, Clinch, P, Hollingworth
openaire   +2 more sources

Laparoscopic Colorectal Surgery in the Era of Robotics: Evolution, Eclipse, or Equilibrium?

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Minimally invasive colorectal surgery has undergone a remarkable transformation over the past three decades. Laparoscopy, once viewed with skepticism, is now firmly established as a standard approach, supported by robust randomized trials demonstrating oncologic safety and improved recovery compared to open surgery.
Amanjeet Singh, Archit Gupta, Azhar Perwaiz, Adarsh Chaudhary   +3 more
wiley   +1 more source

Unveiling research hotspots: a bibliometric study on macrophages in musculoskeletal diseases. [PDF]

Front Immunol
Yue Y, Cao S, Cao F, Wei Y, Li A, Wang D, Liu P, Zeng H, Lin J.   +8 more
europepmc   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

Advanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan, Haicang Zhang, Liping Tong, Di Chen   +3 more
wiley   +1 more source

Wearable Metamaterials with Embodied Intelligence for Programmable Control of Human Limbs Tremor

Advanced Intelligent Systems, EarlyView.
Resulting from alternating muscle contractions, tremors can severely limit human ability to perform everyday tasks like walking or talking, due to their disruptive nature. Medication and surgery may not always effectively address tremor control. A wearable device embodying programmable smart metamaterials with adaptable intelligence to meet the demand ...
Braion Barbosa de Moura, Marcela R. Machado, Tanmoy Mukhopadhyay   +2 more
wiley   +1 more source

Authors’ Response to “Comment on ‘SMPDL3B as a novel biomarker and therapeutic target in myalgic encephalomyelitis’”

Journal of Translational Medicine
Bita Rostami-Afshari, Wesam Elremaly, Anita Franco, Alain Moreau   +3 more
doaj   +1 more source