Results 181 to 190 of about 9,516,409 (390)

Teaching Therapeutic Yoga to Medical Outpatients: Practice Descriptions, Process Reflections, and Preliminary Outcomes [PDF]

, 2006
This article describes therapeutic Yoga practices designed for a medical population with mixed diagnoses and a wide range of health challenges. We present preliminary data from 54 adults who participated in Yoga classes at a community medical center ...
Edwards, Katie M., Gabriel, Kristen, Panico, Richard, Salstrom, Seoka, Spears, Manjula   +4 more
core   +1 more source

LncDARS‐AS1 Regulates ATP1A1 Stability and Enhances Na+/K+ ATPase Activity to Promote Osteosarcoma Metastasis

Advanced Science, EarlyView.
This study identifies LncDARS‐AS1 as a novel oncogenic regulator that stabilizes ATP1A1 and enhances Na⁺/K⁺ ATPase activity, promoting osteosarcoma metastasis. Targeting the LncDARS‐AS1/ATP1A1/NKA axis, including pharmacological inhibition with digoxin, offers promising opportunities for the development of new therapeutic strategies against ...
Mingxian Xu, Jiatian Wei, Xiaoyu Feng, Qinkai Zhang, Jian Chen, Xinyue Wang, Xiudan Zhan, Bing Lu, Weitang Guo, Mingzhe Cheng, Renxuan Huang, Shao Xu, Changye Zou   +12 more
wiley   +1 more source

Disability Insurance, Population Health and Employment in Sweden [PDF]

This paper describes the development of population health and disability insurance utilization for older workers in Sweden and analyses the relation between the two.
Jönsson, Lisa, Palme, Mårten, Svensson, Ingemar   +2 more
core  

Personalized Medication for Chronic Diseases Using Multimodal Data‐Driven Chain‐of‐Decisions

Advanced Science, EarlyView.
A MDD‐CoD is proposed for personalized chronic disease medication. The framework simulates clinical chain‐of‐decisions through three linked deep learning tasks, validated on multi‐center datasets (3 hospitals, 4 diseases), demonstrating enhanced generalization and interpretability in cross‐disease applications.
Xiaoli Chu, Yiheng Ye, Siqiao Tang, Miaoru Han, Guowei Wang, Shuai Lin, Bingzhen Sun, Qingchun Huang, Yan Zhang, Xiaodong Chu, Kun Bao   +10 more
wiley   +1 more source

Patients Prescribed Anakinra for Acute Gout Have Baseline Increased Burden of Hyperuricemia, Tophi, and Comorbidities, and Ultimate All-Cause Mortality. [PDF]

, 2019
Objective:The interleukin-1 (IL-1) receptor antagonist anakinra is an effective, off-label option in acute gout flares, when conventional therapy options are narrowed.
Pedersen, Brian, Sharma, Ena, Terkeltaub, Robert   +2 more
core  

Brachyury‐Activated Fucoidan Hydrogel Microspheres Rejuvenate Degenerative Intervertebral Discs Microenvironment

Advanced Science, EarlyView.
This study describes the creation of injectable Brachyury (Bry) mRNA‐loaded Fucoidan‐functionalized GelMA hydrogel microspheres (BLNP@GF). These microspheres efficiently suppress inflammation, enhance extracellular matrix (ECM) synthesis in degenerated nucleus pulposus cells, and mitigate intervertebral disc degeneration (IVDD) in rat models.
Yuhao Gong, Wenxiao Shi, Xingzhu Liu, Hang Yu, Yinghui Wu, Yanzhang Xia, Caichun Yue, Chongkai Yang, Cong Shen, Renjun Pei, Tianwen Xin, Hailong Pei, Jun Shen   +12 more
wiley   +1 more source

Human iPSCs Derived MSCs‐Secreted Exosomes Modulate Senescent Nucleus Pulposus Cells Induced Macrophage Polarization via Metabolic Reprogramming to Mitigate Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Senescent nucleus pulposus cells drive inflammatory M1 macrophage polarization, exacerbating intervertebral disc degeneration (IDD). Conversely, M1 macrophages accelerate NP cell senescence, creating a vicious cycle. iPSCs‐derived mesenchymal stem cell (iMSCs) exosomes break this loop by delivering miR‐100‐5p to suppress mTORC1/glycolysis in ...
Qian Xiang, Jiawen Zhan, Shuo Tian, Yongzhao Zhao, Zhenquan Wu, Jialiang Lin, Longting Chen, Longjie Wang, Shuai Jiang, Zhuoran Sun, Weishi Li   +10 more
wiley   +1 more source

Allocation of rehabilitation measures provided by the Social Insurance Institution in Finland: A register linkage study [PDF]

, 2007
Hinkka, K, Kivimaki, M, Klaukka, T, Pentti, J, Suoyrjo, H, Vahtera, J   +5 more
core   +1 more source

Repetitive Movements in Melon Cultivation Workers under Greenhouses [PDF]

, 2019
Musculoskeletal disorders cause serious problems that affect workers in many sectors. The objective of this study is the ergonomic analysis of melon cultivation farmers in Almeria-type greenhouses.
Callejón Ferre, Ángel Jesús, Díaz Pérez, Manuel, Golasi, Iacopo, Gómez Galán, Marta, Pérez Alonso, José   +4 more
core   +1 more source

HEALTH DISPARITIES IN RHEUMATIC, MUSCULOSKELETAL, AND SKIN DISEASES: PA-03-054 [PDF]

, 2003

openalex   +1 more source