Results 251 to 260 of about 9,516,409 (390)

Paradoxical Activation of Entheseal Myeloid Cells by JAK1 and Tyk2 Inhibitors via Interleukin‐10 Antagonism

Arthritis &Rheumatology, EarlyView.
Objective JAK inhibition (JAKi) is effective in seronegative spondyloarthropathy (SpA) spectrum disorders, but Tyk2 inhibition failed in SpA spectrum ulcerative colitis, and tofacitinib showed minimal benefit in Crohn disease, which highlights the complex role for JAK/STAT signaling in different inflammatory processes.
Sami Giryes, Chi Wong, Charlie Bridgewood, Mark Harland, Ala Altaie, Nicole McDermott, Kerem Abacar, Abhay Rao, Almas Khan, Tristan McMillan, Peter Loughenbury, Robert Dunsmuir, Vishal Borse, Tom Macleod, Dennis McGonagle   +14 more
wiley   +1 more source

Musculoskeletal diseases, infections and vaccines: state of the art, research perspectives and educational needs. [PDF]

Aging Clin Exp Res
Ecarnot F, Thiyagarajan JA, Barbagallo M, Barratt J, Constantinescu S, Elkayam O, Ferrucci L, Hiligsmann M, Kapetanovic M, Macchia F, Michel JP, Migliore A, Pilotto A, Sieber C, Strangfeld A, Veronese N, Vetrano DL, Maggi S, Rizzoli R.   +18 more
europepmc   +1 more source

Hand Swelling and Other Non–Raynaud Phenomenon Symptoms as the Initial Presentation of Systemic Sclerosis: Prevalence and Clinical Associations in Two US Cohorts

Arthritis &Rheumatology, EarlyView.
Objective Raynaud phenomenon (RP) is often the initial clinical manifestation of systemic sclerosis (SSc), but some patients develop other manifestations first. To help elucidate the diversity of SSc presentation in its early stages, we describe the initial clinical manifestations and antinuclear antibody (ANA) profiles of patients in two early SSc ...
Iqtidar Hanif, Shervin Assassi, Maureen D. Mayes, Zsuzsanna H. McMahan, Meng Zhang, Julio Charles, John M. VanBuren, Jessica S. Alvey, Kimia Ghaffari, Elana J. Bernstein, Flavia V. Castelino, Lorinda Chung, Luke Evnin, Tracy M. Frech, Jessica K. Gordon, Faye N. Hant, Laura K. Hummers, Dinesh Khanna, Kimberly S. Lakin, Dorota Lebiedz‐Odrobina, Yiming Luo, Ashima Makol, Jerry A. Molitor, Duncan F. Moore, Carrie Richardson, Nora Sandorfi, Ami A. Shah, Ankoor Shah, Victoria K. Shanmugam, Virginia D. Steen, Elizabeth R. Volkmann, Carleigh Zahn, Brian Skaug   +32 more
wiley   +1 more source

The associations between sleep problems and pain outcomes in people with hand osteoarthritis – Data from the Nor-hand study

Osteoarthritis and Cartilage Open
Objective: To examine the relation of sleep problems to pain outcomes in people with hand osteoarthritis, and the extent to which central sensitization mediates these relationships.
Daniel H. Bordvik, Pernille Steen Pettersen, Marthe Gløersen, Elisabeth Mulrooney, Tuhina Neogi, Ingvild Kjeken, Ida K. Haugen   +6 more
doaj  

Therapeutic Efficacy of Medicinal Plants with Allopathic Medicine in Musculoskeletal Diseases. [PDF]

Int J Plant Anim Environ Sci
Rajalekshmi R, Agrawal DK.
europepmc   +1 more source

Preventative and therapeutic potential of tocotrienols on musculoskeletal diseases in ageing. [PDF]

Front Pharmacol, 2023
Saud Gany SL, Chin KY, Tan JK, Aminuddin A, Makpol S.   +4 more
europepmc   +1 more source

A Case of Musculoskeletal Tuberculosis Mimicking Adult-Onset Still's Disease [PDF]

, 2014
Jin Kyeong Cho, Min Sung Kim, Jinho Shin, Yeon Sang Jeong, Joon Wan Kim, Jae Phil Choi, Byoong Yong Choi   +6 more
openalex   +1 more source

Identifying Predictive Biomarkers of Response in Patients With Rheumatoid Arthritis Treated With Adalimumab Using Machine Learning Analysis of Whole‐Blood Transcriptomics Data

Arthritis &Rheumatology, EarlyView.
Objective Tumornecrosis factor inhibitors (TNFi) have significantly improved rheumatoid arthritis (RA) management, yet variability in patient response remains a substantial challenge, with approximately 40% of patients discontinuing TNFi due to nonresponse or adverse effects.
Chuan Fu Yap, Nisha Nair, Ann W. Morgan, John D. Isaacs, Anthony G. Wilson, Kimme Hyrich, Guillermo Barturen, María Riva‐Torrubia, Marta Gut, Ivo Gut, Marta E. Alarcón Riquelme, Anne Barton, Darren Plant   +12 more
wiley   +1 more source

The impact of uric acid on musculoskeletal diseases: clinical associations and underlying mechanisms. [PDF]

Front Endocrinol (Lausanne)
Zhang J, Sun N, Zhang W, Yue W, Qu X, Li Z, Xu G.   +6 more
europepmc   +1 more source

Homecare-based motor rehabilitation in musculoskeletal chronic graft versus host disease

, 2011
Andrea Tendas, Larissa Galastri Baraldi, Luca Cupelli, Malgorzata Monika Trawinska, M Ales, M Giovannini, Claudio Cartoni, William Arcese, Pasquale Niscola, Chiara Boschetto, Emiliano Caiazza, R Lentini, Massimiliano Palombi, Luciana Morino, L. Scaramucci, T Dentamaro, Paolo de Fabritiis, F Mandelli   +17 more
openalex   +2 more sources