Alu Overexpression Leads to an Increased Double‐stranded RNA Signature in Dermatomyositis
Objective Dermatomyositis is an autoimmune condition characterized by a high interferon signature of unknown etiology. Because coding sequences constitute <1.2% of our genomes, there is a need to explore the role of the non‐coding genome in disease pathogenesis.
Rayan Najjar +2 more
wiley +1 more source
A bibliometric and visualized analysis of extracellular vesicles in degenerative musculoskeletal diseases (from 2006 to 2024). [PDF]
Yang JJ +6 more
europepmc +1 more source
A phase 2 trial of hydroxychloroquine in individuals at risk for rheumatoid arthritis
Background Individuals with serum elevations of anti‐cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such ‘at‐risk’ individuals. However, hydroxychloroquine (HCQ) is used without supporting clinical trial evidence.
Kevin D. Deane +33 more
wiley +1 more source
Screening and diagnosis of sarcopenia in rheumatic and musculoskeletal diseases: findings from a cross-sectional study. [PDF]
Pardali EC +16 more
europepmc +1 more source
A randomized, placebo‐controlled trial of hydroxychloroquine in incomplete lupus
Objectives Patients with features of systemic lupus erythematosus (SLE) who do not fulfill classification criteria can be designated as incomplete lupus (ILE). This condition includes individuals with a high risk of progression to SLE. Treatment of ILE may reduce symptoms, severity and incidence of SLE. Methods Hydroxychloroquine (HCQ) was chosen as an
Nancy J. Olsen +14 more
wiley +1 more source
Application prospects of urine-derived stem cells in neurological and musculoskeletal diseases. [PDF]
Yang HS +4 more
europepmc +1 more source
Objective Cellular mechanisms driving transition from psoriasis to psoriatic arthritis have remained largely elusive. Thus, we investigated changes within the peripheral blood T cell compartment associated with the transition phase. Methods In an observational study, 116 patients were examined and categorized into subgroups including psoriasis with at ...
Hanna Graßhoff +19 more
wiley +1 more source
Correction: SMPDL3B a novel biomarker and therapeutic target in myalgic encephalomyelitis
Bita Rostami-Afshari +12 more
doaj +1 more source
Methodology Development for Investigating Pathophysiological [18F]-FDG Muscle Uptake in Patients with Rheumatic Musculoskeletal Diseases. [PDF]
Sobejana M +8 more
europepmc +1 more source

