Results 351 to 360 of about 9,385,080 (408)
Heart failure and obesity: Translational approaches and therapeutic perspectives. A scientific statement of the Heart Failure Association of the ESC
European Journal of Heart Failure, EarlyView.Abstract
Obesity and heart failure (HF) represent two growing pandemics. In the general population, obesity affects one in eight adults and is linked with an increased risk for HF. Obesity is even more common in patients with HF, where it complicates the diagnosis of HF and is linked with worse symptoms and impaired exercise capacity. Over the past few Gianluigi Savarese, Gabriele G. Schiattarella, Felix Lindberg, Markus S. Anker, Antoni Bayes‐Genis, Magnus Bäck, Frieder Braunschweig, Chiara Bucciarelli‐Ducci, Javed Butler, Antonio Cannata, Federico Capone, Ovidiu Chioncel, Emilia D'Elia, Arantxa González, Gerasimos Filippatos, Nicolas Girerd, Jean‐Sébastien Hulot, Carolyn S.P. Lam, Lars H. Lund, Christoph Maack, Brenda Moura, Mark C. Petrie, Massimo Piepoli, Abdullah Shehab, Mehmet B. Yilmaz, Peter Seferovic, Carlo G. Tocchetti, Giuseppe M.C. Rosano, Marco Metra +28 morewiley +1 more sourceSeverity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)
Environmental and Molecular Mutagenesis, EarlyView.Abstract
Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White +17 morewiley +1 more sourceSafety of COVID-19 Vaccine in Patients with Rheumatic and Musculoskeletal Diseases. [PDF]
Mediterr J RheumatolYounis AA, Ridha AA, Humadi YA, Jassim NA, Awadh NI, Maroof A, Alqazzaz AMH, Gorial FI, Qaradaghi TA, Abdulzahra ZS, Mahmood ZA, Yaseen NT, AlIdrecy DN, Hakman IT, Tarfah SJ, Khudhair AS. +15 moreeuropepmc +1 more sourceAdvanced Stage Head and Neck Cancer Diagnosis: HEADSpAcE Consortium Health Systems Benchmarking Survey
Head &Neck, EarlyView.ABSTRACT Background
Globally, most people with head and neck cancers (HNCs) are diagnosed with advanced‐stage disease. HNC diagnostic stage has multifactorial explanations, with the role of health system factors not yet fully investigated. Methods
HNC centres (n = 18) from the HEADSpAcE Consortium were surveyed via a bespoke health system questionnaire Grant Creaney, Mariél de Aquino Goulart, Alex McMahon, Claire Paterson, James McCaul, Sandra Perdomo, Laura Mendoza, Laia Alemany, Lidia Maria Rebolho Arantes, Paula Andrea Rodriguez Urrego, Tom Dudding, Mirana Pring, Marta Vilensky, Cecilia Cuffini, Silvia Adriana Lopez de Blanc, José Carlos de Oliveira, Shahid Pervez, Pierre Saintigny, Mauricio Cuello, Jaroslav Betka, Luis Felipe Ribeiro Pinto, Maria Paula Curado, Kazem Zendehdel, Lorenzo Richiardi, Maja Popovic, José Roberto de Podesta, Sandra Ventorin von Zeidler, Ricardo Mai Rocha, HEADSpAcE Consortium, Shaymaa Alwaheidi, Paul Brennan, Shama Virani, Al Ross, David I Conway, R Adam, A Agudo, W Ahrens, L Alemany, S Alibhai, M Angel‐Pavon, N Anwar, L Arantes, P. E. Arantes, L Arguello, Y Avello, L Avondet, A. M. Baldión‐Elorza, C Batista‐Daniel, B Beraldi, B Berenstein, P Bernal, N Bernardino‐Rodrigues, J Betka, K Bilic‐Zimmermann, L Bouvard, M Botta, J Brenes, N Brenner, C Brentisci, C Burtica, M Cabañas, C Canova, E Cantor, G Carretero, A Carvalho, R Carvalho, L Chiusa, P Chopard, M Choulli, Q Chundriger, O Clavero, S Coelho‐Soares‐Lima, I Costa, M Cuello, C Cuffini, M. P. Curado, A. C. de Carvalho, J. C. de Oliveira, T Dias, T Dudding, E Duccini de Souza, I. C. Durant, E Ebrahimi, A Escallón, G. A. Fernandes, B Fervers, V Fiano, F Firme‐Figueira, R Furbino‐Villefort, V Gaborieau, R Gama, M Gangemi, P Garzino‐Demo, R Giglio, A Guasch, J Graça Sant’Anna, M Grega, A Gregório‐Có, M Hadji, J. A. Hakim, N Hayes, C. M. Healy, M Homero de Sá Santos, I Holcatova, K Hurley, M Insfran, G. C. Iorio, M Iqbaluddin Siddiqui, J Johannsen, M Kaňa, J. P. Klussmann, L. P. Kowalski, A Lagiou, P Lagiou, E Legal, J Lenzi, F Luiz Dias, Lyra González, W Machado‐Zorzaneli, G. J. Macfarlane, R Mai‐Rocha, M Maños, P Marinho‐de‐Abreu, J Mckay, C Mena, L Mendoza, E. F. Mendonça, L Meza, B Michels, M. S. Mineiro, C Moccia, P Mongelos, A. L. Montealegre‐Páez, F Morey‐Cortes, A Muñoz, A Ness, A Neves, M Oliva, H Ortiz, J Ortiz, M Osorio, V Ospina, O Ostellino, M Palau, S Paytubi‐Casabona, G Pecorari, S Perdomo, D. M. Pereira, O Pérol, S Pervez, A Pomata, J Polesel, M Popovic, A Poveda, C Prado, K Prager, M Pring, G Ramieri, H Rashidian, S Rasul, J Rego, R. M. Reis, H Renard, L. F. Ribeiro‐Pinto, U Ricardi, L Richiardi, G Riva, P Rodriguez‐Urrego, M Robinson, F Rodilla, I Rodriguez, M Rodríguez, P. E. Roux, T Saeed‐Ali, P Saintigny, J. J. Santivañez, C Scapultampo‐Neto, J Segovia, A Sena, M Sepideh, R Serrano, S. J. Sharma, O Siefer, S Smart, B. P. Sorroche, C Sosa, J. D. Souza, A Stura, S Thomas, S Thoms, O Torres, S Tous, G Ucross, A Valenzuela, J. R. Vasconcelos‐de‐Podestá, M Vilensky, S Von‐Zeidler, T Waterboer, A Whitmarsh, S Wright, K Zendehdel, A Znaor +201 morewiley +1 more source
