Results 91 to 100 of about 90,461 (311)
The Role of Stromal Tumor Environment in Advancing Skin Cancer Diagnosis and Treatment
International Journal of Dermatology, EarlyView.ABSTRACT The stromal tumor environment (STE) plays a vital yet often underrecognized role in cancer progression, shaping tumor development. It influences complex interactions among stromal cells, immune cells, extracellular matrix (ECM) components, and signaling molecules.
Frank Jing +3 more
wiley +1 more source
A single amino acid substitution in the alpha 3 domain of an H-2 class I molecule abrogates reactivity with CTL. [PDF]
, 1987 We previously described a somatic cell expressing a variant H-2Dd molecule that did not serve as a target for alloreactive anti-Dd CTL. The mutant cell line had been isolated by its failure to express a serological epitope present on the H-2Dd alpha 3 ...
Bluestone, JA, Potter, TA, Rajan, TV
core +2 more sources
Journal of Phycology, EarlyView.Abstract Mechanistic elucidation of spore development is essential for understanding reproductive strategies and improving seaweed cultivation. In this study, we isolated a mutant with spore development defects in Pyropia yezoensis (Rhodophyta) from among genetic transformants generated via insertional mutagenesis. We characterized the mutant phenotype
Hikari Izumi +6 more
wiley +1 more source
Mutagen specificity in barley for 1580 eceriferum mutants localized to 79 loci
, 2008 The paper presents 1580 mutants affecting the deposition of epicuticular waxes in cultivated barley and localized to 79 different cer loci. These mutations have been induced by various mutagens: ionizing radiations, organic chemicals, and the inorganic ...
U. Lundqvist, A. Lundqvist
semanticscholar +1 more source
Highly Efficient Site-Specific Mutagenesis in Malaria Mosquitoes Using CRISPR. [PDF]
, 2018 Anopheles mosquitoes transmit at least 200 million annual malaria infections worldwide. Despite considerable genomic resources, mechanistic understanding of biological processes in Anopheles has been hampered by a lack of tools for reverse genetics. Here,
Akbari, Omar S +2 more
core +2 more sources
Molecular Microbiology, EarlyView.A novel TetR‐like regulator (EppR) has been identified to repress genes encoding DNA polymerase V in Acinetobacter baumannii through the direct binding of a conserved EppR motif in their promoters. EppR works with previously identified regulator UmuDAb to serve as co‐regulators of these genes. In response to DNA damage and/or environmental stress, both
Brian Nguyen +6 more
wiley +1 more source
Determination of absorption dose in chemical mutagenesis in plants.
PLoS ONE, 2019 Chemical mutagenesis is a useful tool for inducing mutations in plants. Seeds are often used as the material for chemical mutagenesis. The biological effect of a chemical mutagen on seeds is determined by absorption dose (the product of mutagen ...
Changjiao Ke +7 more
doaj +1 more source
Plant Biotechnology Journal, EarlyView.Summary Fruits with few or no seeds are favoured by consumers because they provide an improved eating experience alongside other important quality traits such as taste and shelf‐life. Gamma irradiation has been widely used to induce favourable trait changes in plants, including a reduction in seediness.
Upuli Nakandala +5 more
wiley +1 more source
Carcinogenesis, 2002 Mutagen sensitivity, measuring the extent of chromosome damage induced by an in vitro treatment of peripheral lymphocytes with bleomycin, has been associated with an increased risk of various human cancers.
J. Tuimala +4 more
semanticscholar +1 more source
Agricultura, 2008 PHENOTIPICAL AND CITOLOGICAL MODIFICATIONS AT SAINFOIN (Onobrychis viiifolia Scop) TREATED WITH GAMMA RAYS In order to make the experiences it was used the “Splendid” sainfoin cultivar, created at USAMV Cluj. To induce the mutations there were used
Elena TĂMAŞ, R. SESTRAŞ, P. RAICA
doaj +1 more source