Results 91 to 100 of about 26,697 (251)

Predicting Drug Interactions and Mutagenicity with Ensemble Classifiers on Subgraphs of Molecules [PDF]

open access: yesarXiv, 2016
In this study, we intend to solve a mutual information problem in interacting molecules of any type, such as proteins, nucleic acids, and small molecules. Using machine learning techniques, we accurately predict pairwise interactions, which can be of medical and biological importance.
arxiv  

Flagellar motility is mutagenic

open access: yesProceedings of the National Academy of Sciences
Flagella are highly complex rotary molecular machines that enable bacteria to not only migrate to optimal environments but also to promote range expansion, competitiveness, virulence, and antibiotic survival. Flagellar motility is an energy-demanding process, where the sum of its production (biosynthesis) and operation (rotation) costs has
Souvik Bhattacharyya   +3 more
openaire   +3 more sources

Thiourea‐Based Compounds Effectiveness Against the Growth of Mycobacterium kansasii: Synthesis, Biological Activity, and Computational Analysis

open access: yesChemistrySelect, Volume 10, Issue 16, April 25, 2025.
Fifty thiourea derivatives are synthesized and evaluated against Mycobacterium kansasii. Compounds 2, 47, and 49 demonstrate potent extra‐ and intracellular activity without causing macrophage cytotoxicity, even against the hypervirulent strains. Structure–activity relationships and in silico analyses highlight favorable molecular features and predict ...
Sanderson Dias Calixto   +13 more
wiley   +1 more source

A perspective of Genes and Environment for the development of environmental mutagen research in Asia

open access: yesGenes and Environment, 2017
Two years have passed since the Japanese Environmental Society (JEMS) made the official journal Genes and Environment (G&E) open access. Current subjects on environmental mutagen research to further advance this field are described herein, and the roles ...
Takashi Yagi
doaj   +1 more source

Software Engineering Practice using Multi-Criteria Decision in Health Care Organizations [PDF]

open access: yesInternational Journal of Management, IT & Engineering Vol. 7 Issue 2, February 2017, ISSN: 2249-0558, 2017
A sound performance of health care organizations depends on vigorous financing system, skilled and well paying personnel, trustworthy information, well sustained health services and reliable technologies they used. The management and organization of health care systems and other health care settings can deeply have an effect on health result ...
arxiv  

Mitochondrial Complex I Molecular Alterations in Sapajus apella as a Human Gastric Carcinogenesis Model After MNU Exposure

open access: yesJournal of Medical Primatology, Volume 54, Issue 2, April 2025.
ABSTRACT Introduction Gastric cancer (GC) remains among the top five global health problems. Therefore, comprehending the tumor energetic behavior is critical to understanding its progression. This study aimed to investigate mitochondrial DNA (mtDNA) alterations in GC cancer cell lines in an animal model.
Bárbara dos Santos Dias   +4 more
wiley   +1 more source

Study on the impact of mutagenic treatment on pollen and spikelet fertility and its relationship in rice (Oryza sativa L.)

open access: yesElectronic Journal of Plant Breeding, 2019
The present study was conducted to study the impact of different mutagens on pollen and spikelet fertility. Pollen fertility and spikelet fertility per cent was found to be inversely proportional to increasing dose of the mutagen in all the treatments ...
M. Akilan   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy