Results 121 to 130 of about 86,136 (325)
A mathematical model of DNA degradation: Possible role of magnetic nanoparticles [PDF]
arXiv, 2007 A mathematical model of genome degradation is proposed that takes into account a variable rate of mutation and increasing number of cells in a developing human organism. The model explains known properties of cancer development, in particular, a synergism between different mutagens and an increased probability of cancer in the early years of life.
arxiv
Building Predictive Models in R Using the caret Package [PDF]
The caret package, short for classification and regression training, contains numerous tools for developing predictive models using the rich set of models available in R.
Max Kuhn
core +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 1993 A two-component transposon system based on the Ac element of maize was used as a mutagen in Arabidopsis thaliana. Transposition of a Ds element marked with a hygromycin-resistance gene was activated from four different locations in the Arabidopsis genome.
David Long +5 more
semanticscholar +1 more source
Mutagen sensitivity: a genetic predisposition factor for cancer.
Cancer Research, 2007 Mutagen sensitivity, measured by quantifying the chromatid breaks induced by mutagens in short-term cultures of peripheral blood lymphocytes, has been used as an indirect measure of DNA repair capacity.
Xifeng Wu, J. Gu, M. Spitz
semanticscholar +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 4, April 2025.A series of benzimidazolium chlorides and their 2‐mercapto were successfully synthesized and characterized. Cytotoxic activity assays revealed that certain synthesized compounds exhibited efficacy against cancer cell lines. To investigate the possible mechanism underlying their cytotoxic effects, the binding interactions of the three most active ...
Mohammad Mavvaji +5 more
wiley +1 more source
EKSTRAK ETANOLIK UMBI KEMBANG SUNGSANG DAN DAUN TAPAK DARA SEBAGAI SUBSITUSI KOLKISIN DALAM MENINGKATKAN PERTUMBUHAN DAN KUALITAS BUAH MELON [PDF]
, 2015 Impor buah melon cukup tinggi karena kebutuhan konsumsi melon meningkat. Untuk mengurangi ketergantungan terhadap buah melon impor ini, maka produksinya perlu ditingkatkan.
Eko , Suprijono +2 more
core
Mutagen sensitivity has high heritability: evidence from a twin study.
Cancer Research, 2006 Despite numerous studies showing that mutagen sensitivity is a cancer predisposition factor, the heritability of mutagen sensitivity has not been clearly established.
Xifeng Wu +9 more
semanticscholar +1 more source
Journal of Medical Primatology, Volume 54, Issue 2, April 2025.ABSTRACT Introduction Gastric cancer (GC) remains among the top five global health problems. Therefore, comprehending the tumor energetic behavior is critical to understanding its progression. This study aimed to investigate mitochondrial DNA (mtDNA) alterations in GC cancer cell lines in an animal model.
Bárbara dos Santos Dias +4 more
wiley +1 more source
Micronucleus induction by 915 MHz Radiofrequency Radiation in Vicia faba root tips [PDF]
arXiv, 2014 The mutagenic effect of radiofrequency electromagnetic field (RF-EMF) is evaluated by the micronucleus (MN) test in secondary roots of Vicia faba seedlings. Root exposures were carried out with 915 MHz continuous wave (CW) radiation for 72h, at power densities of 25, 38, 50 W/m$^2$.
arxiv
The human, F-actin-based cytoskeleton as a mutagen sensor
Cancer Cell International, 2017 Background Forty years ago the actin cytoskeleton was determined to be disrupted in fibroblasts from persons with DNA repair-defective, hereditary colon cancer, with no clear connection between the cytoskeleton and DNA repair defects at that time ...
Nicolette M. Clark +12 more
doaj +1 more source