ABSTRACT African horned melon (Cucumis metuliferus E. Meyer ex Naudin, 2n = 2x = 24) is an under‐researched and under‐utilised cucurbit crop primarily grown for its nutritious fruit. In its centre of diversity, the crop is valued for its relatively high tolerance to insect pests, diseases, drought and heat stress. It is a potential opportunity crop and
Olga Sebati+2 more
wiley +1 more source
Dynamics and bifurcations in a simple quasispecies model of tumorigenesis [PDF]
Cancer is a complex disease and thus is complicated to model. However, simple models that describe the main processes involved in tumoral dynamics, e.g., competition and mutation, can give us clues about cancer behaviour, at least qualitatively, also allowing us to make predictions.
arxiv
Interpreting the dependence of mutation rates on age and time [PDF]
Mutations can arise from the chance misincorporation of nucleotides during DNA replication or from DNA lesions that are not repaired correctly. We introduce a model that relates the source of mutations to their accumulation with cell divisions, providing a framework for understanding how mutation rates depend on sex, age and absolute time. We show that
arxiv
Differential Response of Some Tomato Genes to Base-specific Mutagens [PDF]
H. K. Jain, R. N. Raut
openalex +1 more source
GeoScatt-GNN: A Geometric Scattering Transform-Based Graph Neural Network Model for Ames Mutagenicity Prediction [PDF]
This paper tackles the pressing challenge of mutagenicity prediction by introducing three ground-breaking approaches. First, it showcases the superior performance of 2D scattering coefficients extracted from molecular images, compared to traditional molecular descriptors.
arxiv
Mutation activity of Lonicera caerulea population in an active fault zone (the Altai Mountains) [PDF]
Geophysical and geochemical anomalies may have a mutagenic effect on plants growing in active fault zones being the factors of evolutionary transformation of plant populations. To test this assumption we evaluated the mutation activity of a Lonicera caerulea natural population in one of the active fault zones in the Altai Mountains.
arxiv
A perspective of Genes and Environment for the development of environmental mutagen research in Asia
Two years have passed since the Japanese Environmental Society (JEMS) made the official journal Genes and Environment (G&E) open access. Current subjects on environmental mutagen research to further advance this field are described herein, and the roles ...
Takashi Yagi
doaj +1 more source
Radiomimetic beverages, drugs, and mutagens. [PDF]
Karl Sax, Hally Jolivette Sax
openalex +1 more source
Flagellar motility is mutagenic
Flagella are highly complex rotary molecular machines that enable bacteria to not only migrate to optimal environments but also to promote range expansion, competitiveness, virulence, and antibiotic survival. Flagellar motility is an energy-demanding process, where the sum of its production (biosynthesis) and operation (rotation) costs has
Souvik Bhattacharyya+3 more
openaire +3 more sources
Stacked ensemble\-based mutagenicity prediction model using multiple modalities with graph attention network [PDF]
Mutagenicity is a concern due to its association with genetic mutations which can result in a variety of negative consequences, including the development of cancer. Earlier identification of mutagenic compounds in the drug development process is therefore crucial for preventing the progression of unsafe candidates and reducing development costs.
arxiv