Results 11 to 20 of about 90,461 (311)
Counteracting quasispecies adaptability: extinction of a ribavirin-resistant virus mutant by an alternative mutagenic treatment. [PDF]
BACKGROUND:Lethal mutagenesis, or virus extinction promoted by mutagen-induced elevation of mutation rates of viruses, may meet with the problem of selection of mutagen-resistant variants, as extensively documented for standard, non-mutagenic antiviral ...
Celia Perales+2 more
doaj +1 more source
APOBEC3B enzymes are endogenous carcinogenic mutagens. Metastatic urothelial carcinomas often harbor APOBEC3B-mediated mutations in which tCw to T or G substitution occurs. Here, we evaluated patient survival and CD8+ T-cell density according to APOBEC3B
Hyunho Kim+7 more
doaj +1 more source
Cytogenetic activity of a mutagenic factor with high damaging capacity in winter wheat
The analysis of cytological abnormalities is an important method for identifying the potential of a chemical as a mutagen for future heritable genetic changes, the level of genotype-mutagen interaction and site-specific activity for the nature and/or ...
Vladislav Horshchar, Mykola Nazarenko
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Mutagen resistance and mutation restriction of St. Louis encephalitis virus.
The error rate of the RNA-dependent RNA polymerase (RdRp) of RNA viruses is important in maintaining genetic diversity for viral adaptation and fitness. Numerous studies have shown that mutagen-resistant RNA virus variants display amino acid mutations in
Sara B. Griesemer+6 more
semanticscholar +1 more source
The use of mutagens in plant breeding is used to create new germplasm, increase agricultural yield, quality, and resistance to diseases and pests. Mutagens are physical or chemical factors that can alter the DNA or RNA structure of an organism, causing ...
Aras Türkoğlu+10 more
doaj +1 more source
Antimutagenic and antioxidant activity of a protein fraction from aerial parts of Urtica dioica [PDF]
Context: Urtica dioica L. (Urticaceae), stinging nettle, has been employed as a folklore remedy for a wide spectrum of ailments, including urinary disorders, prostatic hyperplasia, and liver diseases.
DI GIACOMO, Silvia+6 more
core +1 more source
Increased Mutagen Sensitivity and DNA Damage in Pulmonary Arterial Hypertension.
RATIONALE Pulmonary arterial hypertension (PAH) is a serious lung condition characterized by vascular remodeling in the precapillary pulmonary arterioles.
C. Federici+7 more
semanticscholar +1 more source
Induction of Winter Wheat Plant Structure Mutations by Chemomutagenesis
The objectives of our investigations are to describe the variation by muta-tions of stem architecture of the modern Ukrainian winter wheat varieties accord-ing to their interactions with mutagen nature, concentration and genotype-mutagen interaction ...
M. M. Nazarenko
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Low doses of ochratoxin A induce micronucleus formation and delay DNA repair in human lymphocytes [PDF]
The contamination of food commodities by fungal toxins has attracted great interest because many of these mycotoxins are responsible for different diseases, including cancer and other chronic illnesses. Ochratoxin A (OTA) is a mycotoxin naturally present
Barrón-Vivanco, Briscia S.+9 more
core +2 more sources
Етапи створення нового високопродуктивного сорту пшениці м’якої озимої ‘МІП Валенсія’
Мета. Обґрунтувати основні етапи створення високопродуктивного сорту ‘МІП Валенсія’ методом індукованого мутагенезу. Методи. Польові, лабораторні, статистичні.
О. А. Демидов+4 more
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