Results 11 to 20 of about 90,461 (311)

Counteracting quasispecies adaptability: extinction of a ribavirin-resistant virus mutant by an alternative mutagenic treatment. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND:Lethal mutagenesis, or virus extinction promoted by mutagen-induced elevation of mutation rates of viruses, may meet with the problem of selection of mutagen-resistant variants, as extensively documented for standard, non-mutagenic antiviral ...
Celia Perales   +2 more
doaj   +1 more source

Prognostic Impact of APOBEC3B Expression in Metastatic Urothelial Carcinoma and Its Association with Tumor-Infiltrating Cytotoxic T Cells

open access: yesCurrent Oncology, 2021
APOBEC3B enzymes are endogenous carcinogenic mutagens. Metastatic urothelial carcinomas often harbor APOBEC3B-mediated mutations in which tCw to T or G substitution occurs. Here, we evaluated patient survival and CD8+ T-cell density according to APOBEC3B
Hyunho Kim   +7 more
doaj   +1 more source

Cytogenetic activity of a mutagenic factor with high damaging capacity in winter wheat

open access: yesНаукові горизонти, 2023
The analysis of cytological abnormalities is an important method for identifying the potential of a chemical as a mutagen for future heritable genetic changes, the level of genotype-mutagen interaction and site-specific activity for the nature and/or ...
Vladislav Horshchar, Mykola Nazarenko
doaj   +1 more source

Mutagen resistance and mutation restriction of St. Louis encephalitis virus.

open access: yesJournal of General Virology, 2017
The error rate of the RNA-dependent RNA polymerase (RdRp) of RNA viruses is important in maintaining genetic diversity for viral adaptation and fitness. Numerous studies have shown that mutagen-resistant RNA virus variants display amino acid mutations in
Sara B. Griesemer   +6 more
semanticscholar   +1 more source

Ethyl Methanesulfonate (EMS) Mutagen Toxicity-Induced DNA Damage, Cytosine Methylation Alteration, and iPBS-Retrotransposon Polymorphisms in Wheat (Triticum aestivum L.)

open access: yesAgronomy, 2023
The use of mutagens in plant breeding is used to create new germplasm, increase agricultural yield, quality, and resistance to diseases and pests. Mutagens are physical or chemical factors that can alter the DNA or RNA structure of an organism, causing ...
Aras Türkoğlu   +10 more
doaj   +1 more source

Antimutagenic and antioxidant activity of a protein fraction from aerial parts of Urtica dioica [PDF]

open access: yes, 2014
Context: Urtica dioica L. (Urticaceae), stinging nettle, has been employed as a folklore remedy for a wide spectrum of ailments, including urinary disorders, prostatic hyperplasia, and liver diseases.
DI GIACOMO, Silvia   +6 more
core   +1 more source

Increased Mutagen Sensitivity and DNA Damage in Pulmonary Arterial Hypertension.

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2015
RATIONALE Pulmonary arterial hypertension (PAH) is a serious lung condition characterized by vascular remodeling in the precapillary pulmonary arterioles.
C. Federici   +7 more
semanticscholar   +1 more source

Induction of Winter Wheat Plant Structure Mutations by Chemomutagenesis

open access: yesAgrology, 2020
The objectives of our investigations are to describe the variation by muta-tions of stem architecture of the modern Ukrainian winter wheat varieties accord-ing to their interactions with mutagen nature, concentration and genotype-mutagen interaction ...
M. M. Nazarenko
doaj   +1 more source

Low doses of ochratoxin A induce micronucleus formation and delay DNA repair in human lymphocytes [PDF]

open access: yes, 2014
The contamination of food commodities by fungal toxins has attracted great interest because many of these mycotoxins are responsible for different diseases, including cancer and other chronic illnesses. Ochratoxin A (OTA) is a mycotoxin naturally present
Barrón-Vivanco, Briscia S.   +9 more
core   +2 more sources

Етапи створення нового високопродуктивного сорту пшениці м’якої озимої ‘МІП Валенсія’

open access: yesPlant Varieties Studying and Protection, 2018
Мета. Обґрунтувати основні етапи створення високопродуктивного сорту ‘МІП Валенсія’ методом індукованого мутагенезу. Методи. Польові, лабораторні, статистичні.
О. А. Демидов   +4 more
doaj   +1 more source

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