Results 231 to 240 of about 87,443 (291)

Photoactivation of mutagens

Carcinogenesis, 1989
Solutions of several promutagens or of non-genotoxic carcinogens were exposed to sunlight or to artificial sources of UV or fluorescent light, under various experimental conditions. Irradiation resulted in the oxygen-mediated formation of direct-acting mutagenic and DNA-damaging photoproducts in bacteria, with evident structure-activity relationship ...
DE FLORA, SILVIO, CAMOIRANO, ANNA FIORENZA, IZZOTTI, ALBERTO, D'AGOSTINI, FRANCESCO, BENNICELLI, CARLO   +4 more
openaire   +4 more sources

Spanish honeys protect against food mutagen-induced DNA damage.

The Journal of the Science of Food and Agriculture, 2013
BACKGROUND Honey contains a variety of polyphenols and represents a good source of antioxidants, while the human diet often contains compounds that can cause DNA damage.
A. Haza, P. Morales
semanticscholar   +1 more source

Mutagenicity and co-mutagenicity of catechol on salmonella

Mutation Research Letters, 1983
Catechol was not mutagenic for Salmonella typhimurium TA98, TA100 or TA1537 in the presence or absence of S9 mix. At the lower level of S9 in the Ames method, the mutagenic activity of benzo[a]pyrene decreased with the increased addition of catechol.
Daisuke Yoshida, Yōko Fukuhara
openaire   +3 more sources

5-Methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes.

Science, 1990
Direct genomic sequencing revealed that cytosine residues known to have undergone a germ-line mutation in the low density lipoprotein receptor gene or somatic mutations in the p53 tumor suppressor gene were methylated in all normal human tissues analyzed.
William M. Rideout, G. Coetzee, A. Olumi, Peter A. Jones   +3 more
semanticscholar   +1 more source

On the mutagenicity of nitrofurans

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1974
Summary 22 nitrofurans were tested for ability to induce revertants of E. coli WP2 and its uvrA - derivative from tryp - to tryp +. All proved to be mutagnic while two furan analogues (lacking the nitro- group) proved to be inactive. Test strains containing exrA - or recA - genes were not induced to mutate, suggesting that mutants arise in the
Donna Voutsinos, D.R. McCalla
openaire   +3 more sources

Mutagenicity of sulphonylureas

Mutation Research/Genetic Toxicology, 1980
The 11 derivatives of beta-cytotropic sulphonylureas commonly used in the treatment of diabetes mellitus were tested in vivo in the highly sensitive sister-chromatid exchange test. Chlorpropamide and tolbutamide gave a positive reaction with a clear dose-response in Chinese hamsters and mice.
Ruth Münzner, H.W. Renner
openaire   +3 more sources

Mutagenicity of proanthocyanidins

Food and Chemical Toxicology, 1987
Several procyanidins with different degrees of polymerization (dimers, a trimer and a polymer) and extracted from different natural sources were found to be non-mutagenic in the Salmonella mutagenesis assay system. A mutagenic impurity in procyanidin B-4 was isolated by means of reversed-phase high-performance liquid chromatography (HPLC) and ...
C.-L. Yu, B. Swaminathan
openaire   +3 more sources

Mutagenicity of acrylonitrile

Toxicology, 1978
Incubation of Salmonella typhimurium strains in an atmosphere of 0.2% gaseous acrylonitrile increased the numbers of his+ revertants/plate only in the presence of a fortified S9 liver fraction. The mutagenic effect was particularly pronounced with strains TA1530, TA1535 and TA1950 and much weaker with strains TA100, TA98 and TA1978.
F. Poncelet, Michel Mercier, C. de Meester, Marcel Roberfroid   +3 more
openaire   +2 more sources