Results 51 to 60 of about 90,461 (311)
HARMLESS Early Warning System for Advanced Materials
Advanced Sustainable Systems, EarlyView.The HARMLESS Early Warning System tackles Advanced Materials (AdMa) risk governance by providing a framework, organised in two tiers, underpinned with methods/tools to support risk assessors in the pre‐assessment preceding risk assessment. It allows for initial screening to identify AdMa with concerns considering exposure, hazards, sustainability and ...
Julia Prinz +11 more
wiley +1 more source
EFFECT OF GRADEN CRESS (Lepidium sativum) ON CHROMOSOMAL ABERRATIONS AND ITS ANTI - EFFECT ON INDUCTION OF CHROMOSOMAL ABERRATIONS IN WHITE MICE BONE MARROW CELLS USING SHORT – TERM TESTS [PDF]
Mesopotamia Journal of Agriculture, 2009 Effect of garden cress Lepidium sativum (a cruciferous plant) on induction of chromosomal aberrations in bone marrow cells of white mice was studied , in addition to its effect to reverse the chromosomal aberrations induced by drug cyclophosphamide (Cp).
Ilham A. Khalaf
doaj +1 more source
Risk assessment, and carcinogen mutagen for workers potentially exposed in the research laboratories of “Sapienza” University of Rome for Health Surveillance [PDF]
, 2017 The following work is meant to represent the evaluation of risk factors for the health of exposed workers, arising from the management of carcinogenic and mutagenic substances, through the use of algorithms.
Altrudo, Paola +4 more
core +2 more sources
Advanced Science, EarlyView.This study establishes a diesel engine exhaust (DEE)‐induced malignant transformation model in bronchial epithelial cells. Whole genome sequencing（WGS） and RNA‐seq reveal DEE‐induced mutational signatures and gene expression profiles. Mechanistically, DEEaffect polymerase epsilon (POLE) and mismatch repair, driving genomic instability and promoting ...
Pimei Zhang +8 more
wiley +1 more source
Mathematical models of tissue stem and transit target cell divisions and the risk of radiation- or smoking-associated cancer. [PDF]
PLoS Computational Biology, 2017 There is compelling biological data to suggest that cancer arises from a series of mutations in single target cells, resulting in defects in cell renewal and differentiation processes which lead to malignancy.
Mark P Little, Jolyon H Hendry
doaj +1 more source
Enhanced Production of Astaxanthin and Zeaxanthin by Paracoccus Sp. LL1 Through Random Mutagenesis
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Astaxanthin, a high‐value carotenoid with potent antioxidant and anti‐inflammatory activities, is increasingly in demand in various industries. This study reports the successful enhancement of astaxanthin and zeaxanthin production in Paracoccus sp. LL1 through random mutagenesis using ethyl methanesulfonate (EMS).
Anoth Maharjan, Beom Soo Kim
wiley +1 more source
مجلة مركز بحوث التقنيات الاحيائية, 2015 This study was carried out in order to determine the toxic, mutagenic and anti-mutagenic effects for aqueous extract of Vinca rosea dried leaves against the mutagenic effect of Methotrexate (MTX) as a chemical mutagen and Ultra Violet rays (UV) as a ...
Ali Hafedh Abbas Abbas +5 more
doaj +1 more source
The Rosetteless gene controls development in the choanoflagellate S. rosetta. [PDF]
, 2014 The origin of animal multicellularity may be reconstructed by comparing animals with one of their closest living relatives, the choanoflagellate Salpingoeca rosetta.
Greaney, Allison J +3 more
core +1 more source
Intergenerational Enlargement of Human Organs as a Driver of Increased Cancer Risk?
BioEssays, EarlyView.Identifying the environmental factors and associated mechanisms driving increased cancer incidence in younger generations is a matter of great urgency. Here, we propose and discuss a new potential mechanism: larger organ sizes in younger individuals resulting from intergenerational differences in lifestyle, diet, and environmental exposures.
Costas Koufaris, Vicky Nicolaidou
wiley +1 more source
Genes & cancer, 2011 We tallied the number of possible mutant amino acids in proteins thought to be inactivated early in tumorigenesis and in proteins thought to be inactivated late in tumorigenesis, respectively. Proteins thought to be inactivated early in tumorigenesis, on
K. Long +4 more
semanticscholar +1 more source