Results 81 to 90 of about 91,791 (263)

The influence of radio-mimetic chemical mutagen on the chromosomal complex of winter wheat cells

Regulatory Mechanisms in Biosystems, 2017
In this article we report the results of our investigation of cytogenetic parameters of changes in the chromosomal complex of new Ukrainian winter wheat varieties and some relationships between values of cytological indexes and different concentrations ...
M. M. Nazarenko
doaj   +1 more source

EFFECT OF ROCKET JUICE (ERUCA SATIVA ) ON MITOTIC INDEX AND FORMATION OF MICRONUCLEI IN FEMUR BONE MARROW CELLS OF WHITE MICE [PDF]

Mesopotamia Journal of Agriculture, 2008
The effect of orally administered rocket leafs juice on the mitotic index (MI) and micronuclei (Mn) formation was studied in white mice bone marrow . The effect of juice to retarded the abnormalities induced by cyclophosphamide (Cp) administered orally ...
Ilham A. Khalaf
doaj   +1 more source

The In Vitro Transgenic Rodent Assay in Primary MutaMouse Hepatocytes Compared to the Mammalian Cell Gene Mutation Assay Using the HPRT Gene

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert, Kylee Kendra Marie Ronnenberg, Claudia Ruelker, Silke Spang, Naveed Honarvar, Robert Landsiedel   +5 more
wiley   +1 more source

An In Vitro and In Vivo Assessment of the Genotoxic Potential of Maizinol (UP165), a Zea mays Leaf Extract

Journal of Applied Toxicology, EarlyView.
ABSTRACT Benzoxazinoids are secondary metabolites produced in monocotyledons and some dicotyledons from the Acanthaceae, Ranunculaceae, Scrophulariaceae, Plantaginaceae, and Lamiaceae families. Benzoxazinoids are commonly consumed in bread and cereal products that have been ingested for decades, which supports the safe use of benzoxazinoids as food ...
J. Kyle Weston, Barry S. Lynch, James A. Akingbasote   +2 more
wiley   +1 more source

No increase in radiation-induced chromosome aberration complexity detected by m-FISH after culture in the presence of 5’-bromodeoxyuridine [PDF]

, 2006
The thymidine analogue, 5’-bromodeoxyuridine (BrdU), is a known mutagen that is routinely introduced into culture media for subsequent Harlequin stain analysis and determination of cell cycle status.
Anderson, Anderson, Anderson, Anderson, Boei, Cornforth, Dresp, Dudley T. Goodhead, Edwards, George, Goodhead, Griffin, Hawkins, Hsu, Iliakis, Kolin-Gerresheim, Latt, Leonard, Lloyd, Lorimore, Lucas, Moquet, Morimoto, Morton, Natalia D. Sumption, Pala, Perry, Ramsey, Rhona M. Anderson, Ritter, Sachs, Savage, Savage, Schmid, Scott, Simpson, Singleton, Tice, Wang   +38 more
core   +1 more source

Abietic Acid Enhances the Sedative Activity of Diazepam: In vivo Approach along with Receptor Binding Affinity and Molecular Interaction with the GABAergic System

ChemistryOpen, EarlyView.
Abietic acid (AA) reveals potent sedative potential by expressing fast sleeping onset and increased sleeping duration compare to the control group in thiopental sodium induced sleeping mice. The compound also exhibited notable binding affinity (–7.9 kcal/mol) toward GABAA receptors.
Meher Afroz, Rubel Hasan, Mst Muslima Khatun, Mokammel Hossain Tito, Md Shadin, Ranjit Chakma, Mohammed Asiri, Faisal H. Altemani, Abdullah H. Altemani, Md Shimul Bhuia, Muhammad Torequl Islam   +10 more
wiley   +1 more source

B cell activation and affinity discrimination by receptor segregation? [PDF]

, 2005
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Gruhn, T., Iber, D., Lipowsky, R., Maini, P. K.   +3 more
core   +1 more source

Determination of optimum dose of chemical mutagen for large scale seed treatment of white seeded sesame (Sesamum indicum L.) varieties

Electronic Journal of Plant Breeding, 2020
In the present study two white seeded sesame varieties VRI 3 and SVPR 1 were treated with seven different concentration viz., 0.2 %, 0.4 %, 0.6 %, 0.8 %, 1 %, 1.2 % and 1.4 % of chemical mutagen Ethyl Methane Sulphonate (EMS).
V. Sandhiya, M. Kumar, C. Parameswari, C. Vanniarajan, N. Kumaravadivel, N. Sakthivel and Anand M. Badigannavar
doaj   +1 more source

Distribution and activity of nitrate and nitrite reductases in the microbiota of the human intestinal tract

The FEBS Journal, EarlyView.
Nitrate from food is first converted to nitrite by oral bacteria and then further processed in the intestine. The gut microbiota reduces nitrate and nitrite to ammonia or nitric oxide, preventing the formation of carcinogenic nitrosamines. Our analysis highlights Escherichia coli as a key player in this detoxification process, supported by other ...
Natalie Hager, Mélanie Elisabeth Gindt, Marcel Hövels, Jean‐Lou Christian Michel Dorne, Uwe Deppenmeier   +4 more
wiley   +1 more source

In vitro approach to the study of chronic exposure to low doses of x-rays [PDF]

, 2011
El presente trabajo fue realizado con el fin de estudiar el efecto de dosis bajas y repetidas de radiación sobre dos líneas celulares de la misma especie. Se desarrolló un modelo in vitro para evitar la influencia de los factores de confusión que afectan
Peral Garcia, Pilar, Ponzinibbio, Maria Virginia, Seoane, Analia Isabel   +2 more
core   +1 more source