Results 231 to 240 of about 53,897 (283)
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Mutagenicity of proanthocyanidins
Food and Chemical Toxicology, 1987Several procyanidins with different degrees of polymerization (dimers, a trimer and a polymer) and extracted from different natural sources were found to be non-mutagenic in the Salmonella mutagenesis assay system. A mutagenic impurity in procyanidin B-4 was isolated by means of reversed-phase high-performance liquid chromatography (HPLC) and ...
C.-L. Yu, B. Swaminathan
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Toxicology, 1978
Incubation of Salmonella typhimurium strains in an atmosphere of 0.2% gaseous acrylonitrile increased the numbers of his+ revertants/plate only in the presence of a fortified S9 liver fraction. The mutagenic effect was particularly pronounced with strains TA1530, TA1535 and TA1950 and much weaker with strains TA100, TA98 and TA1978.
F. Poncelet +3 more
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Incubation of Salmonella typhimurium strains in an atmosphere of 0.2% gaseous acrylonitrile increased the numbers of his+ revertants/plate only in the presence of a fortified S9 liver fraction. The mutagenic effect was particularly pronounced with strains TA1530, TA1535 and TA1950 and much weaker with strains TA100, TA98 and TA1978.
F. Poncelet +3 more
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Meat‐related mutagens/carcinogens in the etiology of colorectal cancer
Environmental and Molecular Mutagenesis, 2004Diets containing substantial amounts of red or preserved meats may increase the risk of various cancers, including colorectal cancer. This association may be due to a combination of factors such as the content of fat, protein, iron, and/or meat ...
A. Cross, R. Sinha
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Nature, 1972
THERE have been several conflicting reports on the genetic effects of Dichlorvos (2,2-dichlorovinyl dimethyl phosphate), which is the active ingredient of Shell's pesticide, ‘Vapona’.
J. Trevino, M. J. Ashwood-Smith, R. Ring
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THERE have been several conflicting reports on the genetic effects of Dichlorvos (2,2-dichlorovinyl dimethyl phosphate), which is the active ingredient of Shell's pesticide, ‘Vapona’.
J. Trevino, M. J. Ashwood-Smith, R. Ring
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Mutagenicity of radiations and chemical mutagens in Sorghum
Theoretical and Applied Genetics, 1970A comparative study on the relative mutagenicity of radiations (X-and gamma rays) and chemical mutagens (EMS, MMS, dES and NEU) in inducing chlorophyll, viable and total mutations was made on three cultivated varieties (Co. 11, Co. 12 and Co. 18) of Eu-Sorghum. A critical comparison of the chlorophyll, viable and total mutations shows that the mutation
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The Mutagenicity of Dinitrochlorobenzene
Archives of Dermatology, 1985A sample of dinitrochlorobenzene, determined by gas-liquid chromatography and mass spectrometry to be greater than 98% pure, was tested in the Salmonella typhimurium plate assay. The chemical evoked a marked mutagenic response at all concentrations tested (3 to 150 micrograms per plate).
Janette Gerguis +2 more
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A Mutagen is a Mutagen, Not Necessarily a Carcinogen
1986A largely unspoken but underlying assumption that has been made by authors throughout these proceedings is that processes involved in antimutagenesis are related to anticarcinogenesis, a corollary of the somatic mutation theory of carcinogenesis.
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Mutagenicity of oxytetracycline
Mutation Research/Genetic Toxicology, 1983Oxytetracycline hydrochloride, potassium nitrite and a combination of this antibiotic with the nitrite were tested for their mutagenicity in the host-mediated assay with mice as the host animals. The Salmonella typhimurium strain used was his G46. The bacteria were injected intraperitoneally, and the test compounds were administered by a stomach tube ...
Jadwiga Koziorowska +3 more
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On the mutagenicity of nitroimidazoles
Mutation Research/Reviews in Genetic Toxicology, 1981Regarding mutagenicity, metronidazole is one of the best-investigated compounds of the nitroimidazoles. This drug is mutagenic on bacteria, especially if base-pair tester strains are used and bacterial nitroreductases are present. The serum levels attained in man after intake of this drug are sufficient to cause mutations in bacteria.
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Modulation of mutagenicity by phosphorylation of mutagen-metabolizing enzymes
Archives of Biochemistry and Biophysics, 2004In this Minireview, we discuss our findings on phosphorylation of cytochromes P450 (CYP) and influence of this modification on metabolic toxification and/or detoxification of a variety of mutagens. We show that phosphorylation drastically interferes with the mutagenicity of several classes of compounds which are of high human relevance (cytostatic ...
Barbara Oesch-Bartlomowicz, Franz Oesch
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