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Seed viability, germination and seedling growth of canola ( Brassica napus L.) as influenced by chemical mutagens

, 2011
Mutation induction is considered as an effective way to enrich plant genetic variation, particularly for traits with a very low level of genetic variation. The objectives of this study were to evaluate the effect of different dosages of chemical mutagens
P. Nathan   +4 more
semanticscholar   +1 more source

Germ cell mutagens: Risk assessment challenges in the 21st century

Environmental and Molecular Mutagenesis, 2010
Heritable mutations may result in a wide variety of detrimental outcomes, from embryonic lethality to genetic disease in the offspring. Despite this, today's commonly used test batteries do not include assays for germ cell mutation.
Tim Singer, C. Yauk
semanticscholar   +1 more source

Modulation of mutagenicity of various mutagens by lignin derivatives

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2003
The effect of lignin on cytotoxicity, mutagenicity and SOS response induced by 4-nitroquinoline-N-oxide (4NQO), 3-(5-nitro-2-furyl)acrylic acid (5NFAA), 2-nitrofluorene (2NF) as well as hydrogen peroxide was investigated in bacterial assay systems, i.e. the Ames test with Salmonella typhimurium TA98, TA100, TA102 and the SOS chromotest with Escherichia
Božena Košíková   +1 more
openaire   +3 more sources

Anti-mutagenicity of catechin against environmental mutagens

Mutagenesis, 1988
Catechu is the non-mutagenic component of betel quid. We have tested catechu extract and catechin for anti-mutagenic activity in Salmonella typhimurium strain TA98 against environmental mutagens relevant to India. Catechu extract, as well as catechin, shows a dose-dependent decrease in the mutagenicity of tobacco and masheri extracts, and bidi and ...
Sumati V. Bhide, Moolky Nagabhushan
openaire   +3 more sources

Mutagen and anti-mutagen in ginger, Zingiber officinale

Mutation Research Letters, 1982
When rhizome juice of ginger, zingiber officinale, was added to a solution of 2(2-furyl)-3(5-nitro-2-fury)acryl amide (AF2) or N-methyl-N'-nitro-N-nitrosoguanidine (NTG), mutagenesis by these chemicals was markedly increased. As a result of the component fractionation of the ginger juice, it was found that [6]-gingerol was a potent mutagen.
Takeshi Yamamoto, Hakobu Nakamura
openaire   +3 more sources

Fluroxene mutagenicity

Mutation Research/Genetic Toxicology, 1978
The commercially available volatile anesthetic fluroxene (2,2,2-trifluoroethyl vinyl ether) which contains the stabilizer N-phenyl-1-napthylamine, was tested for mutagenicity using four strains of S. typhimurium, TA1535, TA1537, TA98 and TA100, and one strain of E. coli, WP2. In addition, purified fluroxene; N-phenyl-1-napthylamine; trifluoroethanol, a
J M, Baden   +4 more
openaire   +2 more sources

The mutagenicity of saccharin

Mutation Research/Reviews in Genetic Toxicology, 1975
Seventeen different reports are available dealing with the mutagenic effects of saccharin. Many of these are short abstracts, carrying incomplete information. Mainly tested as its sodium salt, saccharin has been found to be weakly mutagenic in Salmonella at very high doses, in Drosophila at moderate doses, and in mice at moderate to high doses.
openaire   +3 more sources

Natural Compounds in the Human Diet and their Ability to Bind Mutagens Prevents DNA–Mutagen Intercalation

Journal of Toxicology and Environmental Health, Part A, 2010
Human diet may contain many mutagenic or carcinogenic aromatic compounds as well as some beneficial physiologically active dietary components, especially plant food phytochemicals, which act as mutagenesis or carcinogenesis inhibitors.
A. Osowski   +3 more
semanticscholar   +1 more source

Infidelity of DNA synthesis in vitro: screening for potential metal mutagens or carcinogens.

Science, 1976
Thirty-one metal salts have been tested for their ability to affect the accuracy of DNA synthesis in vitro. All ten salts of metal carcinogens decreased the fidelity of DNA synthesis.
M. Sirover, L. Loeb
semanticscholar   +1 more source

Metals as Mutagens

1978
A number of metals are mutagenic in bacteria or phage. These include compounds of arsenic, chromium, copper, iron, manganese, molybdenum, platinum, and selenium. Compounds containing alumium, antimony, arsenic, cadmium, copper, lead, mercury, nickel, and tellium have been shown to induce chromosomal aberrations or abnormal cell divisions in animal or ...
openaire   +3 more sources

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