Results 281 to 290 of about 14,999,742 (341)

Learning the language of protein-protein interactions. [PDF]

open access: yesNat Commun
Ullanat V   +3 more
europepmc   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Mitochondrial DNA mutations in head and neck squamous cell carcinoma: a systematic review and meta-analysis. [PDF]

open access: yesBMC Cancer
Mottaghi M   +5 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Changes in intra-host mycovirus population diversity after vertical and horizontal transmission. [PDF]

open access: yesVirus Evol
Peranić K   +7 more
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Genomic characterization of host gene alterations in Theileria annulata-transformed leukocytes. [PDF]

open access: yesCommun Biol
Dandasena D   +10 more
europepmc   +1 more source

Probing the dark energy in the functional protein universe. [PDF]

open access: yesProc Natl Acad Sci U S A
Galpern EA   +4 more
europepmc   +1 more source

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