Results 221 to 230 of about 18,996,847 (344)

A Point Mutation in the RNA Recognition Motif of CSTF2 Associated with Intellectual Disability in Humans Causes Defects in 3′ End Processing [PDF]

, 2020
Petar N. Grozdanov, Elahe Masoumzadeh, Vera M. Kalscheuer, Thierry Bienvenu, Pierre Billuart, Marie-Ange Delrue, Michael P. Latham, Clinton C. MacDonald   +7 more
openalex   +1 more source

Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes. [PDF]

Nat Commun
Uusküla-Reimand L, Lee CA, Oh RH, Klein ZP, Adler N, Akhtar Alvi S, Langille E, Pasini E, Cheng KCL, Serafimova E, Abd-Rabbo D, Hou H, Tsai R, Bhat M, Schramek D, Wilson MD, Reimand J.   +16 more
europepmc   +1 more source

Hotspot propensity across mutational processes

, 2022
Arnedo-Pac C, Muiños F, Gonzalez-Perez A, Lopez-Bigas N.   +3 more
europepmc   +1 more source

The impact of YabG mutations on C. difficile spore germination and processing of spore substrates [PDF]

Morgan S. Osborne, Joshua N. Brehm, Carmen Olivença, Alicia M. Cochran, Mónica Serrano, Adriano O. Henriques, Joseph A. Sorg   +6 more
openalex   +1 more source

Duality for spatially interacting Fleming-Viot processes with mutation and selection [PDF]

, 2011
Donald A. Dawson, Andreas Greven
openalex   +1 more source

Reinforcement Learning for Dynamic Mutation Process Control in Multi-Objective Differential Evolution

, 2022
Lue Tao, Gongshu Wang, Yang Yang, Yun Dong, Li-Jie Su   +4 more
openalex   +1 more source

Mutational Processes Molding the Genomes of 21 Breast Cancers

Cell, 2012
S. Nik-Zainal, Ludmil B. Alexandrov, D. Wedge, Peter Van Loo, Peter Van Loo, C. Greenman, C. Greenman, K. Raine, David Jones, Jonathan Hinton, J. Marshall, L. Stebbings, A. Menzies, Sancha Martin, Kenric Leung, Lina Chen, Catherine Leroy, Manasa Ramakrishna, Richard Rance, K. Lau, L. Mudie, I. Varela, D. Mcbride, G. Bignell, S. Cooke, A. Shlien, John Gamble, I. Whitmore, M. Maddison, P. Tarpey, Helen R Davies, E. Papaemmanuil, P. Stephens, Stuart Mclaren, A. Butler, J. Teague, G. Jönsson, J. Garber, D. Silver, P. Miron, Aquila Fatima, S. Boyault, A. Langerød, A. Tutt, J. Martens, S. Aparicio, Å. Borg, A. Salomon, G. Thomas, A. Børresen-Dale, A. Børresen-Dale, A. Richardson, M. Neuberger, P. Futreal, Peter J. Campbell, Peter J. Campbell, M. Stratton   +56 more
semanticscholar   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Comprehensive analysis of mutational processes across 20 000 adult and pediatric tumors. [PDF]

Nucleic Acids Res
Villa M, Malighetti F, De Sano L, Villa AM, Cordani N, Aroldi A, Antoniotti M, Caravagna G, Graudenzi A, Piazza R, Mologni L, Ramazzotti D.   +11 more
europepmc   +1 more source

Probabilistic Constrained Multiobjective Stochastic Optimization for Industrial Process by Differential Evolution Algorithm with Adaptive Mutation Strategy

Xuliang Li, Mingwei Li, Zhicheng Zhao, Jianan Wang   +3 more
openalex   +1 more source