Results 231 to 240 of about 18,512,812 (309)

Characterisation of the role played by ELMO1, GPR141 and the intergenic polymorphism rs918980 in Fuchs' dystrophy in the Indian population

FEBS Open Bio, EarlyView.
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma, Samar Kumar Basak, Sujata Das, Debasmita Pankaj Alone   +3 more
wiley   +1 more source

A Sticky Multinomial Mixture Model of Strand-Coordinated Mutational Processes in Cancer. [PDF]

iScience, 2020
Sason I, Wojtowicz D, Robinson W, Leiserson MDM, Przytycka TM, Sharan R.   +5 more
europepmc   +1 more source

A unique RNA processing defect and missense mutation in a patient with complete CPSI deficiency

, 1995
Perfusion Suematsu, S Kasbiwagi, Nobuhito Goda, T Sano, Yoko Shinoda   +4 more
openalex   +1 more source

Mutations of the Anti-Müllerian Hormone Gene in Patients with Persistent Müllerian Duct Syndrome: Biosynthesis, Secretion, and Processing of the Abnormal Proteins and Analysis Using a Three-Dimensional Model [PDF]

, 2003
Corinne Belville, Herman van Vlijmen, Christian W. Ehrenfels, Blake Pepinsky, Alireza R. Rezaie, Jean‐Yves Picard, Nathalie Josso, Nathalie di Clemente, Richard L. Cate   +8 more
openalex   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

FEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak   +3 more
wiley   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Mutations in the RNA Binding Domain of Stem-Loop Binding Protein Define Separable Requirements for RNA Binding and for Histone Pre-mRNA Processing

, 2001
Zbigniew Domiński, Judith A. Erkmann, John R. Greenland, William F. Marzluff   +3 more
openalex   +3 more sources

Author Correction: The effects of mutational processes and selection on driver mutations across cancer types. [PDF]

Nat Commun, 2020
Temko D, Tomlinson IPM, Severini S, Schuster-Böckler B, Graham TA.   +4 more
europepmc   +1 more source

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

FEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang   +13 more
wiley   +1 more source

Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations [PDF]

, 2003
Sean Johnson, Jeffrey S. Taylor, L.S. Beese   +2 more
openalex   +1 more source