Results 301 to 309 of about 18,512,812 (309)
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Mutations and Selection in Evolutionary Processes
1991The competition between species in a biological system is analyzed in terms of linear and nonlinear models. The significance of stochastic phenomena in evolutionary processes is emphasized. A qualitative model of evolution as a hopping process on the eigenvalue ladder is developed.
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Abstract IA11: Signatures of mutational processes in human cancer
, 2017All cancers are caused by somatic mutations. These mutations may be the consequence of the intrinsic slight infidelity of the DNA replication machinery, exogenous or endogenous mutagen exposures, enzymatic modification of DNA, or defective DNA repair. In
L. Alexandrov
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Measuring spontaneous deleterious mutation process
1998Parameters of the deleterious mutation process can be estimated using the data on genotypes, phenotypes, or fitnesses. These data can be on long-term evolution, on short-term changes, or on the properties of equilibrium populations. The two most important parameters at the genomic level, the total deleterious mutation rate U and the mutational pressure
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Proof Process Evaluation with Mutation Analysis
2010In the context of deductive proof, formal specification (and thus proofs) may only cover a small part of the program behaviours. We discuss the relevance of applying a mutation analysis, proposed to evaluate the quality of a test set, to evaluate if a specification is able to detect predefined types of faults.
Du Bousquet, Lydie, Lévy, Michel
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The Theory of Rate Processes and Gene Mutation
The Quarterly Review of Biology, 1951W. D. McElroy, C. P. Swanson
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Improved identification of cancer mutational processes
Nature GeneticsTom L. Kaufmann, Roland F. Schwarz
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