Results 231 to 240 of about 1,869,696 (352)

Evaluation of potential of targeted sequencing through mutational signature simulation. [PDF]

PLoS One
Kodama K, Ling Y, Ichikawa H, Wakai T, Okuda S.   +4 more
europepmc   +1 more source

Mutational signature of extracranial meningioma metastases and their respective primary tumors. [PDF]

Acta Neuropathol Commun, 2023
Biczok A, Thorsteinsdottir J, Karschnia P, Ruf VC, Tonn JC, Herms J, Schichor C, Dorostkar MM.   +7 more
europepmc   +1 more source

Supplementary Figures 1-4 from Integrative Analysis of Proteomic Signatures, Mutations, and Drug Responsiveness in the NCI 60 Cancer Cell Line Set

, 2023
Eun Sung Park, Rosalia Rabinovsky, Mark Carey, Bryan T. Hennessy, Roshan Agarwal, Wenbin Liu, Zhenlin Ju, Wanleng Deng, Yiling Lu, Hyun Goo Woo, Sangbae Kim, Jae‐Ho Cheong, Levi A. Garraway, John N. Weinstein, Gordon B. Mills, Ju‐Seog Lee, Michael A. Davies   +16 more
openalex   +2 more sources

Monocyte LOXHD1 and RHOB Expression Predictive of Progressive Systemic Sclerosis–Associated Interstitial Lung Disease

Arthritis Care &Research, EarlyView.
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla, Robert Lafyatis, Kevin F. Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J. Kass   +13 more
wiley   +1 more source

Evidence for a transgenerational mutational signature from ionizing radiation exposure in humans. [PDF]

Sci Rep
Brand F, Klinkhammer H, Knaus A, Holtgrewe M, Weinhold L, Beule D, Ludwig K, Kothiyal P, Maxwell G, Noethen M, Schmid M, Sperling K, Krawitz P.   +12 more
europepmc   +1 more source

A lung-specific mutational signature enables inference of viral and bacterial respiratory niche. [PDF]

Microb Genom, 2023
Ruis C, Peacock TP, Polo LM, Masone D, Alvarez MS, Hinrichs AS, Turakhia Y, Cheng Y, McBroome J, Corbett-Detig R, Parkhill J, Floto RA.   +11 more
europepmc   +1 more source

Combining Three Peripheral Blood Biomarkers to Stratify Rheumatoid Arthritis‐Associated Interstitial Lung Disease Risk

Arthritis Care &Research, Accepted Article.
Objective The purpose was to evaluate a biomarker score consisting of MUC5B rs35705950 promoter variant, plasma matrix metalloproteinase (MMP)‐7, and serum anti‐malondialdehyde‐acetaldehyde (anti‐MAA) antibody for RA‐associated interstitial lung disease risk stratification. Methods Using a multicenter cohort of US veterans with RA, we performed a cross‐
Kelsey Coziahr, Austin M. Wheeler, Brent A. Luedders, Michael Duryee, Halie Frideres, Katherine D. Wysham, Grant W. Cannon, Gary Kunkel, Dana P. Ascherman, Paul A. Monach, Gail S. Kerr, Andreas M. Reimold, Scott M. Matson, Joshua F. Baker, Geoffrey M. Thiele, Ted R. Mikuls, Bryant R. England   +16 more
wiley   +1 more source

Data from Mutational Signature 3 Detected from Clinical Panel Sequencing is Associated with Responses to Olaparib in Breast and Ovarian Cancers

, 2023
Felipe Batalini, D. Gulhan, Victor Y. Mao, Antuan V. Tran, Madeline Polak, Niya Xiong, Nabihah Tayob, Nadine Tung, Eric P. Winer, Erica L. Mayer, Stian Knappskog, Per Eystein Lønning, Ursula A. Matulonis, Panagiotis A. Konstantinopoulos, David B. Solit, Helen Won, Hans Petter Eikesdal, Peter J. Park, Gerburg M. Wulf   +18 more
openalex   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source