Results 171 to 180 of about 84,383 (263)

KRAS driven expression signature has prognostic power superior to mutation status in non-small cell lung cancer [PDF]

, 2017
Á. Nagy, Lőrinc Sándor Pongor, M. Santarpia, Balázs Győrffy   +3 more
openalex   +1 more source

Synthesis of Rhodamine TEMPO Conjugates via Isonitrile‐Based Multicomponent‐Reactions for Mitochondria‐Targeted ROS‐Detection in Cancer Cells

Advanced Sensor Research, EarlyView.
This article explores the development of rhodamine TEMPO conjugates via the Ugi‐multicomponent reaction to detect reactive oxygen species (ROS) in living cells. The sensors are highly selective for mitochondria in both cancer and normal cell lines, with fluorescence quenching and EPR spectroscopy offering precise ROS detection.
Haider N. Sultani, Ibrahim M. Morgan, Hidayat Hussain, Haleh H. Haeri, Dariush Hinderberger, Goran N. Kaluđerović, Bernhard Westermann   +6 more
wiley   +1 more source

Editorial: Mutational signatures and immune response in cancer. [PDF]

Front Genet, 2023
Georgakopoulos-Soares I, Zaravinos A.
europepmc   +1 more source

Combining Mutational Signatures, Clonal Fitness, and Drug Affinity to Define Drug-Specific Resistance Mutations in Cancer [PDF]

, 2018
Teresa Kaserer, Julian Blagg
openalex   +1 more source

Machine Learning‐Driven Multi‐Objective Optimization of Microchannel Reactors for CO₂ Conversion

Advanced Sustainable Systems, EarlyView.
This study introduces a novel method that combines CFD, RSM, and ML to improve a microreactor's performance utilizing the Sabatier reaction. A range of ML models is assessed, and the best one is selected to predict optimal reactor conditions. ML shows the ability to predict performance in just milliseconds, leading to a decrease in computational time ...
Sandeep Kumar, Parmod Kumar, Kuljeet Singh Grewal   +2 more
wiley   +1 more source

The therapeutic significance of mutational signatures from DNA repair deficiency in cancer [PDF]

, 2018
Jennifer Ma, Jeremy Setton, Nancy Y. Lee, Nadeem Riaz, Simon N. Powell   +4 more
openalex   +1 more source

Analysis of Electronic Structure and Binding Energy in Five‐Electron GaAs/AlxGa1‐xAs Quantum Dots Under Penetrable Confinement Potential

Advanced Theory and Simulations, EarlyView.
This study analyses the electronic structure of five‐electron spherical quantum dots with penetrable confinement potential. Spatial confinement and the influence of potential barrier height give rise to the unique properties of quantum dots. These effects lead to profound changes in their energy spectra and optical properties which play a key role in ...
Yusuf Yakar, Bekir Çakır, Ayhan Özmen
wiley   +1 more source

Mesotrypsin Signature Mutation in a Chymotrypsin C (CTRC) Variant Associated with Chronic Pancreatitis

, 2015
András Szabó, Maren Ludwig, Eszter Hegyi, Renata Szépeová, Heiko Witt, Miklós Sahin‐Tóth   +5 more
openalex   +1 more source

The Repertoire of Mutational Signatures in Human Cancer [PDF]

, 2018
Ludmil B. Alexandrov, Jaegil Kim, Nicholas J. Haradhvala, Mi Ni Huang, Alvin Wei Tian Ng, Yang Wu, Arnoud Boot, Kyle R. Covington, Dmitry A. Gordenin, Erik N. Bergstrom, S. M. Ashiqul Islam, Núria López-Bigas, Leszek J. Klimczak, John R. McPherson, Sandro Morganella, Radhakrishnan Sabarinathan, David A. Wheeler, Ville Mustonen, Gad Getz, Steve Rozen, Michael R. Stratton   +20 more
openalex   +1 more source

Autologous Peripheral Vγ9Vδ2 T Cell Synergizes with αβ T Cell Through Antigen Presentation and BTN3A1 Blockade in Immunotherapy of Cervical Cancer

Advanced Science, EarlyView.
This study provides proof‐of‐concept evidence showing that through direct killing, antigen presentation, and competitively binding to BTN3A1, Vγ9Vδ2 T cells amplified from cervical cancer (CC) patients can synergize with αβ T cells to exert anti‐CC function both in vitro and in vivo.
Min Wu, Jian Liu, Liting Liu, Yifan Yang, Hong Liu, Long Yu, Haihong Zeng, Shuo Yuan, Ruiyi Xu, Hangyu Liu, Han Jiang, Shen Qu, Liming Wang, Ying Chen, Jingyu Wang, Yuwei Zhang, Shan He, Ling Feng, Junyan Han, Wanjiang Zeng, Hui Wang, Yafei Huang   +21 more
wiley   +1 more source