Results 221 to 230 of about 77,245 (318)

Supplementary Table 4 from Whole-Exome Sequencing Identifies Mutation Profile and Mutation Signature-Based Clustering Associated with Prognosis in Appendiceal Pseudomyxoma Peritonei

Yu‐Lin Lin, Junqi Zhu, Ruiqing Ma, W Meng, Zi-Yue Wang, Xin-Bao Li, Ru Ma, He‐Liang Wu, Hong-Bin Xu, Ying Gao, Yan Li   +10 more
openalex   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

A redefined InDel taxonomy provides insights into mutational signatures. [PDF]

Nat Genet
Koh GCC, Nanda AS, Rinaldi G, Boushaki S, Degasperi A, Badja C, Pregnall AM, Zhao SJ, Chmelova L, Black D, Heskin L, Dias J, Young J, Memari Y, Shooter S, Czarnecki J, Brown MA, Davies HR, Zou X, Nik-Zainal S.   +19 more
europepmc   +1 more source

Identification of mutational signatures active in individual tumors

, 2017
Sandra Krüger, Rosario M. Piro
openalex   +1 more source

An APOBEC3 Mutational Signature in the Genomes of Human-Infecting Orthopoxviruses

, 2023
Diego Forni, Rachele Cagliani, Uberto Pozzoli, Manuela Sironi   +3 more
openalex   +1 more source

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Investigating the origins of the mutational signatures in cancer. [PDF]

Nucleic Acids Res
Boysen G, Alexandrov LB, Rahbari R, Nookaew I, Ussery D, Chao MR, Hu CW, Cooke MS.   +7 more
europepmc   +1 more source

Mutational Signatures in Gastric Cancer and Their Clinical Implications. [PDF]

Cancers (Basel), 2023
Pužar Dominkuš P, Hudler P.
europepmc   +1 more source

Referee report. For: Decomposition of mutational context signatures using quadratic programming methods [version 1; referees: 1 approved, 1 approved with reservations]

, 2016
Miguel A. Vazquez
openalex   +1 more source

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

Advanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen, Jialin Li, Yan Wu, Han Bao, Xuesong Yang, Guoqing Lv, Ke Ji, Ji Zhang, Xiaojiang Wu, Kai Zhou, Jieli Xu, Jiatian Tang, Xiyuan Han, Anqiang Wang   +13 more
wiley   +1 more source