Results 21 to 30 of about 1,539,409 (267)

Le rôle de l’espace dans le diagnostic et le traitement des “malaises sociaux”. Sur quelques implicites de la politique de la ville en France

open access: yesForum Sociológico, 2007
En France, l’action urbanistique qui vise certains quartiers de banlieues contient de nombreux présupposés qu’on retrouve dans des catégories, des classifications, des notions voire des slogans contribuant à la construction de la rhétorique d’aménagement
Gérard Baudin
doaj   +1 more source

Mutation Analysis of MYORG in a Chinese Cohort With Primary Familial Brain Calcification

open access: yesFrontiers in Genetics, 2021
Primary familial brain calcification (PFBC) is a progressive neurological disorder manifesting as bilateral brain calcifications in CT scan with symptoms as parkinsonism, dystonia, ataxia, psychiatric symptoms, etc. Recently, pathogenic variants in MYORG
Yi-Heng Zeng   +8 more
doaj   +1 more source

« Jeunes des quartiers difficiles » en service civique : du ciblage politique d’un public aux usages juvéniles

open access: yesLien Social et Politiques, 2013
Le service civique, créé par la Loi du 10 mars 2010, estun dispositif public d’incitation à l’engagement.S’adressant aux jeunes âgés de 16 à 25 ans,il leur propose de réaliser des missionsd’intérêt général pour unedurée de 6 à 12 mois en contrepartie d ...
Valérie Becquet
doaj   +1 more source

The herd, a source of flexibility for livestock farming systems faced with uncertainties?

open access: yesAnimal, 2011
‘Adapt to endure’ has become a necessity in agriculture, but the means to do so remain largely undefined. The aim of this literature review is to analyse how the herd contributes to a livestock farming system's capacity to adapt to a changing world and ...
M.O. Nozières, C.H. Moulin, B. Dedieu
doaj   +1 more source

Patterns of mutations in TP53 mutated AML [PDF]

open access: yesBest Practice & Research Clinical Haematology, 2018
TP53 mutated acute myeloid leukemia (AML) responds poorly to chemotherapy and has a short overall survival rate with a median of 5-9 months. Poor outcomes in TP53 mutated AML following chemotherapy have been observed and treatment options remain limited, although the presence of TP53 mutations alone should not be a barrier to therapy.
openaire   +2 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Low host immune pressure may be associated with the development of hepatocellular carcinoma: a longitudinal analysis of complete genomes of the HBV 1762T, 1764A mutant

open access: yesFrontiers in Oncology, 2023
BackgroundIt has been reported that hepatitis B virus (HBV) double mutations (A1762T, G1764A) are an aetiological factor of hepatocellular carcinoma (HCC).
Zhi-Hua Jiang   +11 more
doaj   +1 more source

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille   +9 more
wiley   +1 more source

Genetic polymorphism and phenotypic resistance of Mycobacterium tuberculosis to ofloxacin and moxifloxacin

open access: yesТуберкулез и болезни лёгких, 2020
The objective: to study the phenotypic sensitivity of Mycobacterium tuberculosis (MTB) to fluoroquinolones, ofloxacin and moxifloxacin and correlate it with MTB genome mutations associated with resistance to fluoroquinolones to determine the possibility ...
D. V. Vаkhrushevа   +5 more
doaj   +1 more source

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