Results 41 to 50 of about 3,653,159 (245)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Civil contract as an institution of civil law

Bulletin of Kharkiv National University of Internal Affairs, 2023
The article argues that civil law is a branch of law which regulates property and personal non-property relations between individuals and/or legal entities based on the principles of equality, free expression of will and protection of rights and ...
O. O. Kolobylina
doaj   +1 more source

Mutual recognition schemes [PDF]

, 2015
Australia’s and New Zealand’s mutual recognition schemes are unique in the world by their extensive scope and coverage. They make it easier to do business across borders and give consumers a wider and more competitive range of goods and services ...
Productivity Commission
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

The OECD Dispute Resolution System in Tax Controversies

Laws
The article analyses the latest international tax law developments in dispute resolution settlement protocols and the need for effective multilateral solutions to prevent international double taxation.
Marco Greggi, Anna Miotto
doaj   +1 more source

Navigating Art. 218 TFEU: Third States' Accession to International Conventions and the Position of the EU in This Respect

European Papers, 2022
(Series Information) European Papers - A Journal on Law and Integration, 2022 7(1), 333-343 | European Forum Insight of 22 June 2022 | (Table of Contents) I. Introduction. - II. The scope of art. 218 TFEU. - III. The internal procedure for the conclusion
Paolo Bruno
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

STUDY ABOUT THE DEGREE OF KNOWLEDGE OF THE MEDIATION PROCEDURE AMONG THE RESIDENTS OF RURAL COMMUNITIES IN THE SOUTH MUNTENIA DEVELOPMENT REGION, ROMANIA [PDF]

Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2021
Interhuman relations have experienced many moments of peace, which have favored the emergence of progress, but also moments of unrest, which have led to the emergence of tense phases. It was therefore necessary to develop measures and procedures to bring
Felix Dimitrie CIOCAN, Ioan Niculae ALECU, Ion DONA   +2 more
doaj  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source