Results 41 to 50 of about 37,767 (289)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
DIVORCE BY MUTUAL AGREEMENT AND NOTARY
Pravo, 2019 Divorce by mutual agreement is subject to a court procedure, but in most countries a notarial procedure is applied in the case of a consensual divorce. In this article, the topic of discussion is a conventional divorce, which is characterized by the fact
Tanja Mitrović S.
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Systematic Design Method for Mutual Coupling Reduction in Closely Spaced Patch Antennas
IEEE Open Journal of Antennas and Propagation, 2023 In this article, a systematic design approach is presented to reduce the mutual coupling between a pair of closely spaced microstrip patch antennas (MPAs).
Hui Deng, Lei Zhu, Zhao-An Ouyang
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
5G-IPAKA: An Improved Primary Authentication and Key Agreement Protocol for 5G Networks
Information, 2022 The 3rd generation partnership project (3GPP) has been enhancing the security of the 5G AKA (authentication and key agreement) protocol. However, there may still be some shortcomings in the latest version of the 5G AKA protocol. According to the analysis
Yuelei Xiao, Yang Wu
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Problematika Wakaf dan Penyelesaiannya di Pesantren Al-Falah Limboto Barat Kabupaten Gorontalo
Al-Mizan, 2020 This study aims to uncover the problem of waqf and its solution at Pesantren Al-Falah Limboto Gorontalo. This research is field research, which is descriptive of analytical with the primer data and sekunder data.
Tarnima Zakiyah Rini +1 more
doaj +1 more source