Case Reports in Oncological Medicine, 2019 We previously reported a case of giant cell carcinoma in the lung, in which the use of antiprogrammed death 1 (PD-1) immunotherapy resulted in substantial tumor reduction. In the present study, we describe an additional clinical course.
Tomoo Kakimoto +7 more
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Fixation of an esophageal stent using a novel re‐openable endoclip for a tracheoesophageal fistula
DEN OpenAlthough esophageal stenting is one treatment option as a palliative treatment for tracheoesophageal fistulas, serious complications are associated with stent migration.
Yo Kubota +7 more
doaj +1 more source
Creating an Inclusive Society: Mainstreaming Disability Based on the Social Economy Example [PDF]
, 2007 [Excerpt] This guide, drafted in cooperation with the European Disability Forum (EDF), is one of several initiatives undertaken by the Disability Working Group of the European Standing Conference of Co-operatives, Mutual Societies, Associations and ...
Disability Group, European Disability Forum (EDF) +3 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
State Banking: A Study in Dual Regulation [PDF]
, 1966 We introduce the MATLAB package YALMIP. The purpose of YALMIP is to support rapid definition and solution of LMI problems without the hazzle of learning the syntax in the solvers SP, SOCP and ...
Wille, Frank
core +2 more sources
NONRANDOM GENOTYPIC ASSOCIATIONS IN A LEGUME— BRADYRHIZOBIUM MUTUALISM [PDF]
Evolution, 1996 Genetically divergent lineages often coexist within populations of the annual legume Amphicarpaea bracteata. At one site dominated by two such lineages (termed biotypes "C" and "S"), isolates of root-nodule bacteria (Bradyrhizobium sp.) were sampled from both hosts and analyzed by enzyme electrophoresis.
Jill M, Spoerke +2 more
openaire +2 more sources
A Field Study of the Present Condition of Imabari City\u27s \u27Mujin\u27 Group [PDF]
, 2019 The mutual loan association, the financial means for many ordinary people, was thought to have perished due to the development of the modern financial industry. In some regions, however, it still actually exists.
永井 真也
core +1 more source
Information decomposition of multichannel EMG to map functional interactions in the distributed motor system [PDF]
, 2019 The central nervous system needs to coordinate multiple muscles during postural control. Functional coordination is established through the neural circuitry that interconnects different muscles.
Boonstra, Tjeerd W. +3 more
core +3 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source