Results 71 to 80 of about 5,109,668 (342)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Innovating social connectedness for agricultural innovations in eastern Ethiopia
Cogent Food & Agriculture, 2020 Agricultural innovations can be triggered by the social networks in which farmers have purposefully organized to support themselves. This paper, therefore, explores the values of social connectedness within locally established societies’ mutual support ...
Desalegn Yadeta Wedajo +1 more
doaj +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Rifugiati congolesi in Sudafrica: fra mutuo aiuto e rivendicazioni identitarie
EtnoAntropologia, 2023 At the end of the last century, post-apartheid South Africa opens up to the world and international law on political asylum. At the same time, Mobutu's Zaire collapses.
Stefano Allovio
doaj +2 more sources
Varia História, 2011 El artículo se propone reconstruir y analizar algunas prácticas desarrolladas por las sociedades de socorro mutuo de trabajadores formadas en Tucumán durante el último tercio del siglo XIX y, en especial, desde finales de la década de 1880.
Vanesa Teitelbaum
doaj +1 more source
Selection of Acupoints Combination Based on Pseudo Mutual Information Maximization
IEEE Access, 2020 Acupuncture has been used as an alternative and complementary therapy, however the selection of acupoints combination for a specific disease (or symptoms) highly depends on the experience of acupuncturists.
Jingjing Xu +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Journal of Pharmaceutical Health Care and SciencesBackground Antimicrobial stewardship programs (ASPs) are essential for optimizing antimicrobial use, but many medium-sized hospitals lack infectious disease (ID) specialists.
Keisuke Sawada +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source