Results 241 to 250 of about 1,573,620 (330)

KMT2A alterations in acute myeloid leukemia: a proposed genetic risk model and transplantation outcomes. [PDF]

Exp Hematol Oncol
Chen L, Li J, Zhu Y, Weng X, Huang Y, Zhao L, Yang G, Huang T, An R, Liu Z, Xu X, Chen Y, Huang Q, Wang K, Zhang S.   +14 more
europepmc   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source

Supporting conflict-sensitive, locally-led humanitarianism in Sudan: rebalancing donors' approach to risk. [PDF]

Disasters
Carter B, Satti HA.
europepmc   +1 more source

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication

Advanced Science, EarlyView.
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou, Mingbin He, Jinhong Du, Cong Liu, Weiwei Wang, Yuewen Han, Zhifei Li, Yali Qin, Mingzhou Chen   +8 more
wiley   +1 more source

Value-based large language model agent simulation for mutual evaluation of trust and interpersonal closeness. [PDF]

Sci Rep
Sakamoto Y, Uchida T, Ishiguro H.
europepmc   +1 more source

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

Editorial: Socioeconomic inequalities in digital health. [PDF]

Front Digit Health
Perimal-Lewis L, Correia SV, Sakellari E.   +2 more
europepmc   +1 more source

Computer Aided Verification of Lamport's Fast Mutual Exclusion Algorithm - Using Coloured Petri Nets and Occurrence Graphs with Symmetries

, 1997
Jens Bæk Jørgensen, Lars Michael Kristensen   +1 more
openalex   +2 more sources

Generalized Mechanism Model for Ecosystem Hysteresis

Advanced Science, EarlyView.
A simplified model examines ecosystem transitions into alternative states after disturbances by leveraging positive and negative feedbacks. It identifies critical tipping points and quantifies hysteresis. Tests conducted on lakes, grasslands, and pitcher‐plant leaves align closely with empirical data and enable the prediction of recovery trajectories ...
Yanbin Hao, Xin Wang, Jie Liu, Mingzi Wu, Jianqing Du, Kai Xue, Xiaoning Song, Xiaoyong Cui, Tong Zhao, Yanfen Wang   +9 more
wiley   +1 more source

A study of the relationship between mutual aid and the mental health of older people. [PDF]

BMC Public Health
Liu X, Zheng L, Li M, Hu B.
europepmc   +1 more source