Results 121 to 130 of about 2,467,903 (217)

Metabolites stratify future major depressive disorder risk in obese population: a longitudinal machine learning analysis. [PDF]

Psychol Med
Zhai X, Xing A, Deng Y, Lam CK, Wang L, Yu H, Tong HHY, Lourenço N, Zhao L, Li K.   +9 more
europepmc   +1 more source

Diamond jubilee of the Mercantile Mutual Insurance Co. Ltd., 1878-1938.

, 1938
Caption title.; Cover title: 1878-1938 to commemorate the diamond jubilee of the managing director's service with the Mercantile Mutual Insurance Co. Ltd.; Electronic reproduction. Canberra, A.C.T.
Mercantile Mutual Insurance Company.
core  

Dual‐Organelle Secretome Conjugation and Organ‐Uptake Tracking (DuO‐SCOUT) Enables Deep and Sensitive Mapping of the Secreted Proteins

Advanced Science, EarlyView.
A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang, Rui Qian, Jiaxing Song, Xingqi Meng, Jin Young Kim, Kwok On Lai, Li Wang, Liang Zhang   +7 more
wiley   +1 more source

Evaluating microbial network inference methods: moving beyond synthetic data with reproducibility-driven benchmarks. [PDF]

BMC Bioinformatics
Ghaeli Z, Aghdam R, Eslahchi C.
europepmc   +1 more source

An Interpretable, Data‐Driven, Hierarchical Multi‐Domain Fusion Framework for Classification and Motor Function Scoring in Chronic Ankle Instability

Advanced Science, EarlyView.
An AI‐enabled digital twin framework integrates wearable EMG sensing with hierarchical multi‐domain fusion to classify chronic ankle instability, distinguish clinically relevant subtypes, and generate continuous motor function scores. Clinically interpretable functional stratification and SHAP‐based biomarker analysis provide transparent decision ...
Tianle Jie, Datao Xu, Zhifeng Zhou, Bas Van Hooren, Huiyu Zhou, Yi Yuan, Xiangli Gao, Monèm Jemni, Liangliang Xiang, Meizi Wang, Justin Fernandez, Tibor J. Goda, Yaodong Gu   +12 more
wiley   +1 more source

Genomic landscape and clinical characteristics of ERBB2/HER2-mutated colorectal cancers. [PDF]

Oncologist
Aksu MD, Peniche PZ, Baytar DK, Jambunathan B, Jan YJA, Hsieh R, Rahman S, Krauss JC, Veenstra CM, Sahin IH.   +9 more
europepmc   +1 more source

Klotho‐Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A

Advanced Science, EarlyView.
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang, Shihui Lin, Tianyu Wu, Zhixin Zhang, Hong Zhou, Xue Hong, Youhua Liu   +6 more
wiley   +1 more source

P-KNN: joint calibration of multiple pathogenicity prediction tools streamlines variant classification. [PDF]

Genet Med
Lin PY, Brandes N.
europepmc   +1 more source

Highly Sensitive Spatial Host‐Microbiome Transcriptomics in FFPE Tissues via Iterative Hydrogel Expansion

Advanced Science, EarlyView.
Ex‐spRandom is a spatial transcriptomics platform that synergizes random‐primed chemistry with iterative hydrogel expansion. By physically decrowding the dense FFPE matrix, this scalable technology shatters the traditional resolution‐sensitivity barrier.
Shunji Zhang, Mengyuan Wang, Jiaye Chen, Yuyi Zhu, Bin Zhu, Ziye Xu, Yuan Liao, Yongcheng Wang   +7 more
wiley   +1 more source

Explainable artificial intelligence for postoperative analgesia risk stratification and clinical decision support in abdominal surgery. [PDF]

Front Digit Health
Wang MH, Jian J, Wu J.
europepmc   +1 more source