Results 61 to 70 of about 418,048 (310)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

STABILITAS KINERJA REKSADANA SYARIAH DALAM MENGHADAPI GEJOLAK MAKRO EKONOMI

open access: yesIndonesian Journal of Islamic Literature and Muslim Society, 2020
Islamic mutual funds as one of the financial investment products in Indonesia experienced rapid development in the last 5 years. Several studies have shown that the performance of a financial investment product is influenced by the macroeconomic ...
M. Rahmawan Arifin, Muhammad Alan Nur
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Mutual fund governance and fund performance

open access: yesCorporate Ownership and Control, 2008
The increased wealth invested in mutual funds and recent scandals at many fund firms have led to increased scrutiny of mutual fund governance. We examine measures of the strength of mutual fund governance and the relation of these measures to fund performance.
openaire   +1 more source

Investment Styles, Fees, & Returns Among Individually Managed & Team Managed Mutual Funds [PDF]

open access: yes, 2011
Identifying a successful mutual fund investment involves a crucial analysis of alternatives, all of which influence the true benefit of the investment.
Cehanowicz, Kendal
core   +1 more source

Mutual funds' ownership and firm performance: Evidence from China [PDF]

open access: yes, 2008
Mutual funds have emerged and rapidly developed since 2000 in China. This study tests empirically the impact of mutual funds' ownership on firm performance in China, using a large sample for the period of 2001-2005.
Xiao, JZ, Yuan, R, Zou, H
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

THE PERFORMANCE OF MUTUAL FUNDS IN SLOVAKIA

open access: yesВісник Київського національного університету імені Тараса Шевченка. Серія Економіка, 2016
A good indicator for the financial markets performance in different countries is the evolution of mutual funds in terms of their inflows and outflows. The goal of the present paper is to analyse the performance of the mutual funds in Slovakia.
F. Tudorache, L. Nicolescu, L. Belascu
doaj   +1 more source

Does Concurrent Management of Mutual Funds and Pension Plans Create Conflicts of Interest?

open access: yesEnsayos de Economía, 2020
The purpose of this paper is to compare the performance of mutual funds —pension plans— whose managers simultaneously manage the assets belonging to pension plans —mutual funds— with that achieved by mutual funds —pension plans— whose managers only ...
Carmen Pilar Martí Ballester
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

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