Results 91 to 100 of about 19,913 (185)
Experimental Physiology, EarlyView.Abstract Previous work in younger adults has shown that during small muscle mass exercise, the tolerable degree of neuromuscular impairment at task failure is greater than during large muscle mass exercise. However, no study has compared the neuromuscular responses to small and large muscle mass exercise whilst matching exercise modality in older ...
Emily Dodd, Callum G. Brownstein
wiley +1 more source
High concentrations of Maraviroc do not alter immunological and metabolic parameters of CD4 T cells
Scientific ReportsMaraviroc (MVC) is an antiretroviral drug capable of binding to CCR5 receptors and block HIV entry into target cells. Moreover, MVC can activate NF-kB pathway and induce viral transcription in HIV-infected cells, being proposed as a latency reversal ...
Erick De La Torre Tarazona +4 more
doaj +1 more source
Common inputs to motor units are modulated by force profile and muscle length
Experimental Physiology, EarlyView.Abstract Groups of motor units receive common synaptic inputs from specialized networks of premotor neurons to produce movement. Here, we test whether common inputs received by motor units in the first dorsal interosseous are fixed or task‐dependent during submaximal isometric contractions.
Abdulkerim Darendeli +3 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract EMG‐based muscle force predictions are often inaccurate following active muscle stretch or shortening because of residual force enhancement (rFE) or depression (rFD), respectively, which can alter the neural drive to a muscle. However, the extent of neural drive modulation attributable to rFE or rFD remains unknown owing to the limited spatial
Brent James Raiteri +4 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma +12 more
wiley +1 more source
Neuromuscular fatigability with repeated exercise in hypoxia: From single‐joint paradigms to sprints
The Journal of Physiology, EarlyView.Abstract figure legend Acute hypobaric or normobaric hypoxic exposure accelerates neuromuscular fatigability during repeated exercise. Indices of peripheral and central fatigue are not different at exhaustion in mild, moderate and severe hypoxia compared with normoxia, but task failure occurs earlier.
Luca Ruggiero +5 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend In healthy young males, we found that skeletal muscle hypertrophy following a period of resistance exercise training (RET) was consistent within and between subjects, as assessed using a variety of established methods. The skeletal muscle hypertrophic response was independent of external load.
Matthew J. Lees +11 more
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The Journal of Physiology, EarlyView.Abstract figure legend We investigated how 6 weeks of dynamic knee‐extensor interval training with blood flow restriction (BFR‐leg) and without (CTRL‐leg) impacts performance and its mechanisms using non‐invasive methods. Specifically, we used gold‐standard methods to assess neuromuscular function, vascular function using Doppler ultrasound, and near ...
Colin Lavigne +5 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Activation of both the metaboreflex via post‐exercise circulatory occlusion and the chemoreflex via acute and chronic hypoxia increased pulmonary artery systolic pressure. Coactivation of these reflexes further increased pulmonary artery pressure in an additive manner.
Lauren E. Maier +13 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Participants completed cycling exercise with (placebo) and without (25 µg intrathecal fentanyl) intact group III/IV muscle afferent feedback in three settings: normoxia, acute hypoxia and chronic hypoxia after 7–9 days of acclimatisation (∼3800 m). Blocking afferent feedback suppressed exercise hyperpnoea across all environments,
Elliott J. Jenkins +23 more
wiley +1 more source