Results 91 to 100 of about 19,309 (219)

The influence of metaboreflex activation on pulmonary pressure with combined chemoreflex activation in acute and chronic hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Activation of both the metaboreflex via post‐exercise circulatory occlusion and the chemoreflex via acute and chronic hypoxia increased pulmonary artery systolic pressure. Coactivation of these reflexes further increased pulmonary artery pressure in an additive manner.
Lauren E. Maier, Elliott J. Jenkins, Andrew Douglas, Jack Talbot, Alexandra Williams, Jonathan Moore, Craig D. Steinback, Liam D. Corr, Zoe H. Adams, Fabio Giuseppe Laginestra, Markus Amann, Philip N. Ainslie, Travis D. Gibbons, Mike Stembridge   +13 more
wiley   +1 more source

High concentrations of Maraviroc do not alter immunological and metabolic parameters of CD4 T cells

Scientific Reports
Maraviroc (MVC) is an antiretroviral drug capable of binding to CCR5 receptors and block HIV entry into target cells. Moreover, MVC can activate NF-kB pathway and induce viral transcription in HIV-infected cells, being proposed as a latency reversal ...
Erick De La Torre Tarazona, Caroline Passaes, Santiago Moreno, Asier Sáez-Cirión, José Alcamí   +4 more
doaj   +1 more source

The role of group III/IV afferent feedback in the ventilatory, pressor and metabolic responses to exercise in normoxia and hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Participants completed cycling exercise with (placebo) and without (25 µg intrathecal fentanyl) intact group III/IV muscle afferent feedback in three settings: normoxia, acute hypoxia and chronic hypoxia after 7–9 days of acclimatisation (∼3800 m). Blocking afferent feedback suppressed exercise hyperpnoea across all environments,
Elliott J. Jenkins, Phuong L. Ha, Connor A. Howe, Jay M. J. R. Carr, Justin A. Monteleone, Andrew J. M. Douglas, Abigail Nicholson, Andrew Steele, Brydie Lemkes, Jodie L. Koep, L. Madden Brewster, Jennifer Duffy, Mathew I. B. Debenham, Tena Monaghan, Declan Isaak, Jacob McCormick, Brian H. Dalton, Chris J. McNeil, Jared Baylis, David MacLeod, Mike Stembridge, Markus Amann, Philip N. Ainslie, Travis D. Gibbons   +23 more
wiley   +1 more source

Transcranial direct current stimulation enhances delayed retention after 5 days of lower‐limb motor skill learning

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the 5 day lower‐limb motor skill learning protocol combining ankle visuomotor practice with transcranial direct current stimulation (tDCS). Participants were allocated to motor skill practice with active tDCS over the leg representation of primary motor cortex (SKILL‐STIM), motor skill practice with sham ...
August Lomholt Kvistad, Lasse Jespersen, Jonas Rud Bjørndal, Lasse Christiansen, Anke Ninija Karabanov, Jesper Lundbye‐Jensen   +5 more
wiley   +1 more source

Genomic profiling of Mexican patients with B‐cell precursor acute lymphoblastic leukemia reveals clinically significant somatic and potential germline variants

The Journal of Pathology: Clinical Research, Volume 12, Issue 5, September 2026.
Abstract B‐cell precursor acute lymphoblastic leukemia (preB‐ALL) is characterized by pathogenic variants currently used in precision oncology. However, the mutational landscape of Mexican children with preB‐ALL has not yet been thoroughly explored and defined in terms of the clinical significance.
Daniel Martínez Anaya, María del Rocío Juárez‐Velázquez, Ulises Juárez Figueroa, Michael Dean, Consuelo Salas Labadía, Marian Valladares Coyotecatl, Adriana Reyes León, Norma López Santiago, Luis Juárez Villegas, Marta Zapata Tarrés, Patricia Pérez‐Vera   +10 more
wiley   +1 more source

Insights Into Soil Health in Sugarcane From a Bibliometric Analysis: Brazil's Scientific Contribution to the World

GCB Bioenergy, Volume 18, Issue 9, September 2026.
This bibliometric review (2000–2025) reveals a sharp increase in publications and citations on sugarcane soil health after 2010, driven by mechanized harvesting and climate–bioenergy policies. Research is spatially concentrated in São Paulo State and dominated by chemical and physical indicators, with biological attributes remaining underrepresented ...
Lucas Jónatan Rodrigues da Silva, Miriam Büchler Tarumoto, Oziel Cereja Neves, Lilybeth Namie Tomita, Douglas Gonçalves Saraiva, Dirceu de Mattos Junior, Claudia Barros Monteiro‐Vitorello, Márcio R. Nunes, João de Andrade Bonetti, Carlos Alexandre Costa Crusciol   +9 more
wiley   +1 more source

Neuromuscular Fatigue and Perceived Fatigability in the Hours Following a High‐Intensity Endurance Running Depend on the Exercise Protocol

European Journal of Sport Science, Volume 26, Issue 8, August 2026.
ABSTRACT This study investigated neuromuscular fatigue and perceived fatigability across different high‐intensity endurance running protocols. Twelve males (mean ± SD; V˙O2max $\dot{\mathrm{V}}{\mathrm{O}}_{2\,\max }$: 52.2 ± 6.9 mL/kg/min) ran ∼8.0 km: (i) at the velocity associated to the respiratory compensation point (vRCP; 5 × 8 min bouts ‒ RUN100%
Yago Medeiros Dutra, Paloma Tavares Mendonça, Stuart Goodall, Alessandro Moura Zagatto   +3 more
wiley   +1 more source

Impact of cenobamate on cortical responses to transcranial magnetic stimulation in people with drug‐resistant focal epilepsy

Epilepsia Open, Volume 11, Issue 4, Page 1171-1183, August 2026.
Abstract Objective Cenobamate (CNB) is an effective antiseizure medication, though its mechanisms of efficacy remain incompletely understood. We assessed changes in cortical responses to transcranial magnetic stimulation (TMS) following CNB treatment.
Silvano R. Gefferie, Diego Jiménez‐Jiménez, Gerhard H. Visser, Robert M. Helling, Arn M. J. M. van den Maagdenberg, Josemir W. Sander, Simona Balestrini, Roland D. Thijs   +7 more
wiley   +1 more source

Propofol‐induced hypertriglyceridemia in critically ill trauma patients requiring nutrition therapy: A descriptive cohort study

Journal of Parenteral and Enteral Nutrition, Volume 50, Issue 6, Page 794-804, August 2026.
Abstract Background This study aimed to assess the incidence and identify risk factors associated with the development of propofol‐induced hypertriglyceridemia in critically ill trauma patients who required nutrition therapy. Methods Adult patients (aged >17 years) admitted to the trauma intensive care unit who received propofol for >24 h and had a ...
Emma S. Lemke, Jonathon K. Walker, Julie E. Farrar, Saskya Byerly, Dina M. Filiberto, Roland N. Dickerson   +5 more
wiley   +1 more source

Addressing the distressing: Pancreatic enzyme replacement therapy mitigates abdominal symptoms and weight loss during chemotherapy for advanced pancreatic cancer: A prospective study

Nutrition in Clinical Practice, Volume 41, Issue 4, Page 1157-1165, August 2026.
Abstract Background Pancreatic enzyme insufficiency (PEI) contributes to symptom burden and malnutrition in advanced pancreatic cancer (aPC). We aimed to evaluate the impact of pancreatic enzyme replacement therapy (PERT) on symptom burden and weight during chemotherapy.
Pamela N. Klassen, Christina A. Kim, Jessica Kasnik, Michael B. Sawyer, Sunita Ghosh, Vickie Baracos, Vera C. Mazurak   +6 more
wiley   +1 more source