Results 11 to 20 of about 172 (90)

Complications of Endoscopic Pressure Study Integrated System: Review of 1205 Cases in 10 Years' Experience. [PDF]

DEN Open
ABSTRACT Background and Aims The Endoscopic Pressure Study Integrated System (EPSIS) is a novel endoscopic tool to assess lower esophageal sphincter (LES) function by monitoring intragastric pressure (IGP) through insufflation. While previous studies have confirmed its diagnostic utility for LES dysfunction‐related disorders such as gastroesophageal ...
Iwasaki M, Tanaka I, Inoue H, Saino M, Ushikubo K, Yamamoto K, Nishikawa Y, Owada K, Abiko S, Tanabe M.   +9 more
europepmc   +2 more sources

Utility of the Endoscopic Pressure Study Integrated System in Identifying Silent Gastroesophageal Reflux Disease During Routine Health Check-ups. [PDF]

DEN Open
ABSTRACT Objectives The endoscopic pressure study integrated system (EPSIS) is a novel functional endoscopic modality that records intragastric pressure (IGP) waveforms during CO2 insufflation to evaluate lower esophageal sphincter (LES) function and diagnose gastroesophageal reflux disease (GERD).
Nishikawa Y, Inoue H, Yamamoto K, Sakurai T, Okada Y, Ushikubo K, Shigeta K, Tanaka I, Abiko S, Tanabe M, Ito T, Yokoyama N, Uragami N.   +12 more
europepmc   +2 more sources

Myocardial Perfusion Defects in Hypertrophic Cardiomyopathy Mutation Carriers

Journal of the American Heart Association, EarlyView., 2021
Background Impaired myocardial blood flow (MBF) in the absence of epicardial coronary disease is a feature of hypertrophic cardiomyopathy (HCM). Although most evident in hypertrophied or scarred segments, reduced MBF can occur in apparently normal segments.
Rebecca K. Hughes, Claudia Camaioni, João B. Augusto, Kristopher Knott, Ellie Quinn, Gabriella Captur, Andreas Seraphim, George Joy, Petros Syrris, Perry M. Elliott, Saidi Mohiddin, Peter Kellman, Hui Xue, Luis R. Lopes, James C. Moon   +14 more
wiley   +1 more source

A Snowfall Detection Algorithm for Fengyun-3D Microwave Sounders with Differentiated Atmospheric Temperature Conditions

, 2023
Precipitation in different phases has varying effects on runoff. However, monitoring surface snowfall poses a significant challenge, highlighting the importance of developing a snowfall detection algorithm.
Jintao Xu, Qingwen Ji, Songkun Yan, Xiaoqing Li, Ziqiang Ma   +4 more
core   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source

Considerations for drug trials in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant, Matthias Schmitt, Anna B. Reid, Clifford J. Garratt, William G. Newman, Aneil Malhotra, Rhys Beynon, Masliza Mahmod, Betty Raman, Robert M. Cooper, Dana Dawson, Thomas Green, Sanjay K. Prasad, Anvesha Singh, Susanna Dodd, Hugh Watkins, Stefan Neubauer, Christopher A. Miller   +17 more
wiley   +1 more source

A phenomap of TTR amyloidosis to aid diagnostic screening

ESC Heart Failure, Volume 12, Issue 2, Page 1113-1118, April 2025.
Abstract Cardiac amyloidosis due to transthyretin (ATTR) remains an underdiagnosed cause of cardiomyopathy. As awareness of the disease grows and referrals for ATTR increase, clinicians are likely to encounter more atypical forms of the condition in clinical practice.
Alexios S. Antonopoulos, Theodoros Tsampras, George Lazaros, Konstantinos Tsioufis, Charalambos Vlachopoulos   +4 more
wiley   +1 more source

Testing VIPV Curved Modules: Methods and Challenges

Progress in Photovoltaics: Research and Applications, EarlyView.
This work presents procedures and equipment for characterizing curved vehicle‐integrated photovoltaic (VIPV) modules through STC I–V curve and relative angular response (RAR) measurements. Outdoor measurements are compared with indoor measurements obtained using a collimated‐light solar simulator, showing excellent agreement for STC I–V curves.
Ricardo Moruno, Francisco Martín, Juan Manuel Redondo, Javier Malo, Luis J. San José, Guido Vallerotto, Steve Askins, Rubén Núñez, César Domínguez, Ignacio Antón, Rebeca Herrero   +10 more
wiley   +1 more source

Influence of Sex and Diagnosis on Clinical Variables and Neurocognitive Performance in Severe Mental Illness. Results From the PsyCourse Study

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Bipolar disorder (BD) and schizophrenia (SZ) are serious mental illnesses (SMI) with overlapping symptoms but distinct differences in onset and course. Sex differences are an area of growing interest in SMI. This study aims to examine potential interactions between sex and diagnosis across a broad range of variables, to compare ...
Maria Serra‐Navarro, Maria Heilbronner, Brisa Solé, Roger Borràs, Anabel Martinez‐Arán, Kristina Adorjan, Alba Navarro‐Flores, Mojtaba Oraki Kohshour, Daniela Reich‐Erkelenz, Eva C. Schulte, Fanny Senner, Ion‐George Anghelescu, Volker Arolt, Bernhard T. Baune, Udo Dannlowski, Detlef E. Dietrich, Andreas J. Fallgatter, Christian Figge, Markus Jäger, Georg Juckel, Carsten Konrad, Jens Reimer, Eva Z. Reininghaus, Max Schmauß, Andrea Schmitt, Carsten Spitzer, Jens Wiltfang, Jörg Zimmermann, Sergi Papiol, Urs Heilbronner, Peter Falkai, Thomas G. Schulze, Eduard Vieta, Carla Torrent, Monika Budde, Silvia Amoretti   +35 more
wiley   +1 more source

Effect of Intramuscular Adrenaline on Histamine‐Induced Hypotension: A Randomised Placebo‐Controlled Pilot Trial

Allergy, EarlyView.
Histamine infusions induce reproducible severe hypotension. Intramuscular adrenaline showed ‘supposedly therapeutic’ plasma concentrations but did not produce a sustained clinically relevant improvement in shock in the majority of recipients. These findings question adrenaline pharmacokinetic surrogate thresholds and support the need for faster and ...
Matthias Weiss‐Tessbach, Al Medina Dizdarevic, Thorsten Bischof, Christa Firbas, Alexander Taschner, Eva‐Luise Ritter‐Hobl, Barbara Steinlechner, Eva Fischer, Lorenz Sonnberger, Georg Gelbenegger, Jolanta M. Siller‐Matula, Christian Schoergenhofer, Bernd Jilma   +12 more
wiley   +1 more source