Results 121 to 130 of about 114,353 (299)

Vaccinations During Pregnancy Protect the Mother–Infant Dyad and Are Generally Safe

Acta Paediatrica, EarlyView.
ABSTRACT Aim Vaccination in pregnancy has a critical impact on mothers, foetuses and infants. The aim of this paper was to summarise key points presented by experts attending the 12th Maria Delivoria‐Papadopoulos Perinatal Symposium in March 2025 and further expand and update them.
Ariadne Malamitsi‐Puchner, Despina D. Briana, Gian Carlo Di Renzo   +2 more
wiley   +1 more source

Critical role of the mast cell/tryptase/PAR2 axis in anastrozole‐induced pain

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Anastrozole, an aromatase inhibitor, is used to treat postmenopausal women with hormone receptor‐positive breast cancer, but also induces musculoskeletal pain and can lead to therapeutic regimen suspension. Aromatase inhibitors promote the release of pro‐inflammatory substances from sensitised nerve fibres, which might ...
Maria Fernanda Pessano Fialho, Raquel Tonello, Evelyne Silva Brum, Gabriela Becker, Nigel W. Bunnett, Sara Marchesan Oliveira   +5 more
wiley   +1 more source

Rheumatological Manifestations in People Living with Human T-Lymphotropic Viruses 1 and 2 (HTLV-1 and HTLV-2) in Northern Brazil

Viruses
Human T-lymphotropic virus 1 (HTLV-1) infection has been associated with inflammatory, autoimmune, and lymphoproliferative diseases with a wide spectrum of clinical manifestations.
Márcio Yutaka Tsukimata, Bianca Lumi Inomata da Silva, Leonn Mendes Soares Pereira, Bruno José Sarmento Botelho, Luciana Cristina Coelho Santos, Carlos David Araújo Bichara, Gabriel dos Santos Pereira Neto, Aline Cecy Rocha Lima, Francisco Erivan da Cunha Rodrigues, Natália Pinheiro André, Sarah Marques Galdino, Danniele Chagas Monteiro, Ludmila do Carmo de Souza Silva, Lourena Camila Oliveira Araújo, José Ronaldo Matos Carneiro, Rosana de Britto Pereira Cruz, Ricardo Ishak, Antonio Carlos Rosário Vallinoto, Bárbara Nascimento de Carvalho Klemz, Izaura Maria Vieira Cayres Vallinoto   +19 more
doaj   +1 more source

TNF‐α partially modulates the endothelial dysfunction during the acute phase of Trypanosoma cruzi infection

British Journal of Pharmacology, EarlyView.
Background and Purpose Whereas the effects of Trypanosoma cruzi (T. cruzi) infection are well‐characterised in the heart, its impact on the vasculature has received little attention. In this study, we investigated the effects of acute and chronic T. cruzi infection on vascular responsiveness and the underlying mechanisms.
Thales M. H. Dourado, Wanessa M. C. Awata, Gustavo F. Pimenta, Barbara M. Marchetti, Maiara V. Providello, Sérgio De Albuquerque, Carlos R. Tirapelli   +6 more
wiley   +1 more source

Some evidences about Crimean Congo Hemorrhagic Fever [PDF]

, 2008
[No abstract ...
Abbasi, A., Besharat, S., Jabbari, A.
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Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, EarlyView.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Pharmacotherapeutics of Musculoskeletal Orofacial Pain

Journal of the California Dental Association
Background Musculoskeletal orofacial pain is an umbrella term for pain in the masticatory muscles, temporomandibular joint and their associated tissues.
Brian E. Cairns, Sujay A. J. Mehta
doaj   +1 more source

Impact of Sequential Ramucirumab Plus Docetaxel After PD‐1 Inhibitors on Anti‐PD‐1 Antibody‐Bound T‐Cell Dynamics and Clinical Outcomes

Cancer Science, EarlyView.
Ramucirumab (RAM) plus docetaxel (DOC) after PD‐1 inhibitors showed clinical activity, with responders exhibiting maintained anti–PD‐1 (IgG4+)‐bound CD8+ T cells and decreased IgG4+ Tregs. A sequential strategy of administering RAM plus DOC during persistent anti–PD‐1 antibody binding may be beneficial in patients with advanced non‐small cell lung ...
Kinnosuke Matsumoto, Yujiro Naito, Takayuki Shiroyama, Motohiro Tamiya, Kazumi Nishino, Akihiro Tamiya, Kyoichi Okishio, Yuhei Kinehara, Tomoki Kuge, Masahide Mori, Shingo Satoh, Hidekazu Suzuki, Satoshi Tetsumoto, Toshie Niki, Yasuhiko Suga, Akio Osa, Toshiyuki Minami, Shohei Koyama, Yoshito Takeda, Nobuyuki Takakura, Atsushi Kumanogoh   +20 more
wiley   +1 more source

Musculoskeletal Disorders in Patients on Statin Therapy: Prospective and Observational Study at a Tertiary Care Hospital

Journal of Clinical and Preventive Cardiology
Aims and Objectives: To determine the incidence, spectrum, and predictors of musculoskeletal (MSK) disorders among patients initiated on statins.
Mushtaq Ahmad Dangroo, Haris Shamas, Muzaffar Ahmad Bindroo, Fayaz Ahmad Sofi, Feroze Shaheen, Nahida Majid, Suhaib Shamas, Hilal Ahmad Rather   +7 more
doaj   +1 more source

EPI Update, August 6, 2010 [PDF]

, 2010
Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...

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