Results 131 to 140 of about 114,353 (299)

Testing the feasibility of an intermittent low‐energy diet in women with gestational diabetes

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims The study aimed to assess feasibility, acceptability and safety of an ILED in a randomised controlled trial of ILED vs. best NHS care healthy diet and exercise advice in women with Gestational Diabetes Mellitus (GDM) with body mass index ≥27.5 kg/m2 (≥25 kg/m2 in high‐risk minority ethnic groups) in the last trimester of pregnancy ...
Elizabeth Dapre   +11 more
wiley   +1 more source

A Tale of Two Conditions: 50 Years of Chronic Illness and Cancer From a Nursing Perspective

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Introduction In this commentary, I consider the disparity between the care we see as a necessity for cancer patients and the lack of care we afford to many persons with chronic disease. Background I ground my arguments in my own clinical practice and research experiences over a 50‐year period augmented by reference to available literature ...
Sally Thorne
wiley   +1 more source

Efficacy and safety of ME3183, an oral phosphodiesterase 4 inhibitor, in patients with plaque psoriasis

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
We assessed four different doses of ME3183, a novel phosphodiesterase 4 inhibitor, and placebo in 132 patients with moderate to severe plaque psoriasis. At Week 16, more patients receiving ME3183 achieved ≥75% reduction in baseline Psoriasis Area and Severity Index scores than those receiving placebo, with no new safety concerns.
Kim A. Papp   +5 more
wiley   +1 more source

Benefit of immune checkpoint inhibitors as adjuvant treatment for acral melanomas

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
When questioning the effectiveness of adjuvant immunotherapy for acral melanomas, we found no clinical benefit to the adjuvant proposal, despite the maintenance of adverse effects. Abstract Background Solar factors play no role in the development of acral melanoma (AM). AM is characterized by low cumulative solar damage (low CSD).
Damien Sanogo   +13 more
wiley   +1 more source

Occlusal Sensitivity to Articulating Foils in Patients With Temporomandibular Disorders and Healthy Controls

open access: yesJournal of Oral Rehabilitation, EarlyView.
Using articulating foils of varying thickness, occlusal tactile acuity was compared between patients with chronic painful temporomandibular disorders (TMDp) and healthy controls. TMDp patients showed enhanced detection of thinner foils and greater perceptual sensitivity, accompanied by a more liberal decision strategy, whereas higher frequencies of ...
Iva Z. Alajbeg   +5 more
wiley   +1 more source

Does acetaminophen activate endogenous pain inhibition in chronic fatigue syndrome/fibromyalgia and rheumatoid arthritis? : a double-blind randomized controlled cross-over trial [PDF]

open access: yes, 2013
Background: Although enhanced temporal summation (TS) and conditioned pain modulation (CPM), as characteristic for central sensitization, has been proved to be impaired in different chronic pain populations, the exact nature is still unknown. Objectives:
De Clerck, Luc   +10 more
core   +1 more source

Brief Diagnostic Criteria for Temporomandibular Disorders (Tmd): Enhancing Sensitivity in Diagnosing Headache Attributed to Tmd (A Multi‐Centre Study)

open access: yesJournal of Oral Rehabilitation, EarlyView.
This multicentre retrospective study evaluated reintroducing selected DC/TMD examination items into the bDC/TMD to improve diagnosis of headache attributed to TMD. Reintroducing temple headache confirmation (E1b) markedly increased diagnostic sensitivity while maintaining high inter‐examiner reliability, supporting refinement and validation of the ...
Nykänen Laura   +12 more
wiley   +1 more source

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